| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATP2C1 | ATP2C2 | ENSP00000376914 | ENSP00000262429 | ATPase, Ca++ transporting, type 2C, member 1 | ATPase, Ca++ transporting, type 2C, member 2; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium (By similarity) | 0.903 |
| ATP2C1 | SLC50A1 | ENSP00000376914 | ENSP00000357389 | ATPase, Ca++ transporting, type 2C, member 1 | solute carrier family 50 (sugar transporter), member 1; Mediates sugar transport across membranes. May stimulate V(D)J recombination by the activation of RAG1 | 0.417 |
| ATP2C2 | ATP2C1 | ENSP00000262429 | ENSP00000376914 | ATPase, Ca++ transporting, type 2C, member 2; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium (By similarity) | ATPase, Ca++ transporting, type 2C, member 1 | 0.903 |
| ATP2C2 | SLC50A1 | ENSP00000262429 | ENSP00000357389 | ATPase, Ca++ transporting, type 2C, member 2; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium (By similarity) | solute carrier family 50 (sugar transporter), member 1; Mediates sugar transport across membranes. May stimulate V(D)J recombination by the activation of RAG1 | 0.415 |
| DCP1B | SLC50A1 | ENSP00000280665 | ENSP00000357389 | DCP1 decapping enzyme homolog B (S. cerevisiae); May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7-methyl guanine cap structure from mRNA molecules, yielding a 5’-phosphorylated mRNA fragment and 7m-GDP (By similarity) | solute carrier family 50 (sugar transporter), member 1; Mediates sugar transport across membranes. May stimulate V(D)J recombination by the activation of RAG1 | 0.512 |
| IVL | SLC50A1 | ENSP00000357753 | ENSP00000357389 | involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia (By similarity) | solute carrier family 50 (sugar transporter), member 1; Mediates sugar transport across membranes. May stimulate V(D)J recombination by the activation of RAG1 | 0.800 |
| RAG1 | SLC50A1 | ENSP00000299440 | ENSP00000357389 | recombination activating gene 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between t [...] | solute carrier family 50 (sugar transporter), member 1; Mediates sugar transport across membranes. May stimulate V(D)J recombination by the activation of RAG1 | 0.610 |
| RPS5 | SLC50A1 | ENSP00000196551 | ENSP00000357389 | ribosomal protein S5 | solute carrier family 50 (sugar transporter), member 1; Mediates sugar transport across membranes. May stimulate V(D)J recombination by the activation of RAG1 | 0.812 |
| SLC50A1 | ATP2C1 | ENSP00000357389 | ENSP00000376914 | solute carrier family 50 (sugar transporter), member 1; Mediates sugar transport across membranes. May stimulate V(D)J recombination by the activation of RAG1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.417 |
| SLC50A1 | ATP2C2 | ENSP00000357389 | ENSP00000262429 | solute carrier family 50 (sugar transporter), member 1; Mediates sugar transport across membranes. May stimulate V(D)J recombination by the activation of RAG1 | ATPase, Ca++ transporting, type 2C, member 2; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium (By similarity) | 0.415 |
| SLC50A1 | DCP1B | ENSP00000357389 | ENSP00000280665 | solute carrier family 50 (sugar transporter), member 1; Mediates sugar transport across membranes. May stimulate V(D)J recombination by the activation of RAG1 | DCP1 decapping enzyme homolog B (S. cerevisiae); May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7-methyl guanine cap structure from mRNA molecules, yielding a 5’-phosphorylated mRNA fragment and 7m-GDP (By similarity) | 0.512 |
| SLC50A1 | IVL | ENSP00000357389 | ENSP00000357753 | solute carrier family 50 (sugar transporter), member 1; Mediates sugar transport across membranes. May stimulate V(D)J recombination by the activation of RAG1 | involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia (By similarity) | 0.800 |
| SLC50A1 | RAG1 | ENSP00000357389 | ENSP00000299440 | solute carrier family 50 (sugar transporter), member 1; Mediates sugar transport across membranes. May stimulate V(D)J recombination by the activation of RAG1 | recombination activating gene 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between t [...] | 0.610 |
| SLC50A1 | RPS5 | ENSP00000357389 | ENSP00000196551 | solute carrier family 50 (sugar transporter), member 1; Mediates sugar transport across membranes. May stimulate V(D)J recombination by the activation of RAG1 | ribosomal protein S5 | 0.812 |
| SLC50A1 | SULT2B1 | ENSP00000357389 | ENSP00000201586 | solute carrier family 50 (sugar transporter), member 1; Mediates sugar transport across membranes. May stimulate V(D)J recombination by the activation of RAG1 | sulfotransferase family, cytosolic, 2B, member 1; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol, and isoform 2 avidly sulfonates pregnenolone but not cholesterol | 0.561 |
| SLC50A1 | SUMF2 | ENSP00000357389 | ENSP00000341938 | solute carrier family 50 (sugar transporter), member 1; Mediates sugar transport across membranes. May stimulate V(D)J recombination by the activation of RAG1 | sulfatase modifying factor 2 | 0.540 |
| SLC50A1 | TLCD2 | ENSP00000357389 | ENSP00000331965 | solute carrier family 50 (sugar transporter), member 1; Mediates sugar transport across membranes. May stimulate V(D)J recombination by the activation of RAG1 | TLC domain containing 2 | 0.499 |
| SLC50A1 | TRPV2 | ENSP00000357389 | ENSP00000342222 | solute carrier family 50 (sugar transporter), member 1; Mediates sugar transport across membranes. May stimulate V(D)J recombination by the activation of RAG1 | transient receptor potential cation channel, subfamily V, member 2; Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH | 0.609 |
| SULT2B1 | SLC50A1 | ENSP00000201586 | ENSP00000357389 | sulfotransferase family, cytosolic, 2B, member 1; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol, and isoform 2 avidly sulfonates pregnenolone but not cholesterol | solute carrier family 50 (sugar transporter), member 1; Mediates sugar transport across membranes. May stimulate V(D)J recombination by the activation of RAG1 | 0.561 |
| SUMF2 | SLC50A1 | ENSP00000341938 | ENSP00000357389 | sulfatase modifying factor 2 | solute carrier family 50 (sugar transporter), member 1; Mediates sugar transport across membranes. May stimulate V(D)J recombination by the activation of RAG1 | 0.540 |
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