CEP85L protein (Homo sapiens) - STRING network view

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Score

CEP85L

centrosomal protein 85kDa-like (808 aa)

Predicted Functional Partners:

MARK2

0.740

SLC35F1

0.470

CDC42BPG

0.455

RBM34

0.418

FAM133B

0.410

WRAP73

0.407

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42BPG	CEP85L	ENSP00000345133	ENSP00000357474	CDC42 binding protein kinase gamma (DMPK-like); May act as a downstream effector of CDC42 in cytoskeletal reorganization. Contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and thus MLC2 phosphorylation (By similarity)	centrosomal protein 85kDa-like	0.455
CEP85L	CDC42BPG	ENSP00000357474	ENSP00000345133	centrosomal protein 85kDa-like	CDC42 binding protein kinase gamma (DMPK-like); May act as a downstream effector of CDC42 in cytoskeletal reorganization. Contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and thus MLC2 phosphorylation (By similarity)	0.455
CEP85L	FAM133B	ENSP00000357474	ENSP00000398401	centrosomal protein 85kDa-like	family with sequence similarity 133, member B	0.410
CEP85L	MARK2	ENSP00000357474	ENSP00000385751	centrosomal protein 85kDa-like	MAP/microtubule affinity-regulating kinase 2; Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. Phosphorylates CRTC2/TORC2, DCX, HDAC7, KIF13B, MAP2, MAP4, MAPT/TAU, and RAB11FIP2. Plays a key role in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Regulates epithelial cell polarity by phosphorylating RAB11FIP2. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity an [...]	0.740
CEP85L	RBM34	ENSP00000357474	ENSP00000386226	centrosomal protein 85kDa-like	RNA binding motif protein 34	0.418
CEP85L	SLC35F1	ENSP00000357474	ENSP00000353557	centrosomal protein 85kDa-like	solute carrier family 35, member F1; Putative solute transporter (Potential)	0.470
CEP85L	WRAP73	ENSP00000357474	ENSP00000270708	centrosomal protein 85kDa-like	WD repeat containing, antisense to TP73	0.407
FAM133B	CEP85L	ENSP00000398401	ENSP00000357474	family with sequence similarity 133, member B	centrosomal protein 85kDa-like	0.410
MARK2	CEP85L	ENSP00000385751	ENSP00000357474	MAP/microtubule affinity-regulating kinase 2; Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. Phosphorylates CRTC2/TORC2, DCX, HDAC7, KIF13B, MAP2, MAP4, MAPT/TAU, and RAB11FIP2. Plays a key role in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Regulates epithelial cell polarity by phosphorylating RAB11FIP2. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity an [...]	centrosomal protein 85kDa-like	0.740
RBM34	CEP85L	ENSP00000386226	ENSP00000357474	RNA binding motif protein 34	centrosomal protein 85kDa-like	0.418
SLC35F1	CEP85L	ENSP00000353557	ENSP00000357474	solute carrier family 35, member F1; Putative solute transporter (Potential)	centrosomal protein 85kDa-like	0.470
WRAP73	CEP85L	ENSP00000270708	ENSP00000357474	WD repeat containing, antisense to TP73	centrosomal protein 85kDa-like	0.407

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