node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BIRC5 | NUS1 | ENSP00000301633 | ENSP00000357480 | baculoviral IAP repeat containing 5 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae); Acts as a specific receptor for the N-terminus of Nogo- B, a neural and cardiovascular regulator. Regulates the stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol | 0.800 |
C2orf18 | CDS1 | ENSP00000345528 | ENSP00000295887 | chromosome 2 open reading frame 18; Involved in the maintenance of mitochondrial membrane potential in pancreatic ductal adenocarcinoma (PDAC) cells. Promotes pancreatic ductal adenocarcinoma (PDAC) cell growth. May play a role as a nucleotide-sugar transporter | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1; Provides CDP-diacylglycerol an important precursor for the synthesis of phosphatidylinositol (PtdIns), phosphatidylglycerol, and cardiolipin. Overexpression may amplify cellular signaling responses from cytokines. May also play an important role in the signal transduction mechanism of retina and neural cells | 0.726 |
C2orf18 | CDS2 | ENSP00000345528 | ENSP00000419879 | chromosome 2 open reading frame 18; Involved in the maintenance of mitochondrial membrane potential in pancreatic ductal adenocarcinoma (PDAC) cells. Promotes pancreatic ductal adenocarcinoma (PDAC) cell growth. May play a role as a nucleotide-sugar transporter | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 | 0.726 |
C2orf18 | NUS1 | ENSP00000345528 | ENSP00000357480 | chromosome 2 open reading frame 18; Involved in the maintenance of mitochondrial membrane potential in pancreatic ductal adenocarcinoma (PDAC) cells. Promotes pancreatic ductal adenocarcinoma (PDAC) cell growth. May play a role as a nucleotide-sugar transporter | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae); Acts as a specific receptor for the N-terminus of Nogo- B, a neural and cardiovascular regulator. Regulates the stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol | 0.707 |
CDS1 | C2orf18 | ENSP00000295887 | ENSP00000345528 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1; Provides CDP-diacylglycerol an important precursor for the synthesis of phosphatidylinositol (PtdIns), phosphatidylglycerol, and cardiolipin. Overexpression may amplify cellular signaling responses from cytokines. May also play an important role in the signal transduction mechanism of retina and neural cells | chromosome 2 open reading frame 18; Involved in the maintenance of mitochondrial membrane potential in pancreatic ductal adenocarcinoma (PDAC) cells. Promotes pancreatic ductal adenocarcinoma (PDAC) cell growth. May play a role as a nucleotide-sugar transporter | 0.726 |
CDS1 | EPRS | ENSP00000295887 | ENSP00000355890 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1; Provides CDP-diacylglycerol an important precursor for the synthesis of phosphatidylinositol (PtdIns), phosphatidylglycerol, and cardiolipin. Overexpression may amplify cellular signaling responses from cytokines. May also play an important role in the signal transduction mechanism of retina and neural cells | glutamyl-prolyl-tRNA synthetase | 0.580 |
CDS1 | NUS1 | ENSP00000295887 | ENSP00000357480 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1; Provides CDP-diacylglycerol an important precursor for the synthesis of phosphatidylinositol (PtdIns), phosphatidylglycerol, and cardiolipin. Overexpression may amplify cellular signaling responses from cytokines. May also play an important role in the signal transduction mechanism of retina and neural cells | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae); Acts as a specific receptor for the N-terminus of Nogo- B, a neural and cardiovascular regulator. Regulates the stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol | 0.712 |
CDS2 | C2orf18 | ENSP00000419879 | ENSP00000345528 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 | chromosome 2 open reading frame 18; Involved in the maintenance of mitochondrial membrane potential in pancreatic ductal adenocarcinoma (PDAC) cells. Promotes pancreatic ductal adenocarcinoma (PDAC) cell growth. May play a role as a nucleotide-sugar transporter | 0.726 |
CDS2 | EPRS | ENSP00000419879 | ENSP00000355890 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 | glutamyl-prolyl-tRNA synthetase | 0.592 |
CDS2 | NUS1 | ENSP00000419879 | ENSP00000357480 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae); Acts as a specific receptor for the N-terminus of Nogo- B, a neural and cardiovascular regulator. Regulates the stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol | 0.712 |
EPRS | CDS1 | ENSP00000355890 | ENSP00000295887 | glutamyl-prolyl-tRNA synthetase | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1; Provides CDP-diacylglycerol an important precursor for the synthesis of phosphatidylinositol (PtdIns), phosphatidylglycerol, and cardiolipin. Overexpression may amplify cellular signaling responses from cytokines. May also play an important role in the signal transduction mechanism of retina and neural cells | 0.580 |
EPRS | CDS2 | ENSP00000355890 | ENSP00000419879 | glutamyl-prolyl-tRNA synthetase | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 | 0.592 |
EPRS | NUS1 | ENSP00000355890 | ENSP00000357480 | glutamyl-prolyl-tRNA synthetase | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae); Acts as a specific receptor for the N-terminus of Nogo- B, a neural and cardiovascular regulator. Regulates the stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol | 0.672 |
NUS1 | BIRC5 | ENSP00000357480 | ENSP00000301633 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae); Acts as a specific receptor for the N-terminus of Nogo- B, a neural and cardiovascular regulator. Regulates the stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol | baculoviral IAP repeat containing 5 | 0.800 |
NUS1 | C2orf18 | ENSP00000357480 | ENSP00000345528 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae); Acts as a specific receptor for the N-terminus of Nogo- B, a neural and cardiovascular regulator. Regulates the stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol | chromosome 2 open reading frame 18; Involved in the maintenance of mitochondrial membrane potential in pancreatic ductal adenocarcinoma (PDAC) cells. Promotes pancreatic ductal adenocarcinoma (PDAC) cell growth. May play a role as a nucleotide-sugar transporter | 0.707 |
NUS1 | CDS1 | ENSP00000357480 | ENSP00000295887 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae); Acts as a specific receptor for the N-terminus of Nogo- B, a neural and cardiovascular regulator. Regulates the stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1; Provides CDP-diacylglycerol an important precursor for the synthesis of phosphatidylinositol (PtdIns), phosphatidylglycerol, and cardiolipin. Overexpression may amplify cellular signaling responses from cytokines. May also play an important role in the signal transduction mechanism of retina and neural cells | 0.712 |
NUS1 | CDS2 | ENSP00000357480 | ENSP00000419879 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae); Acts as a specific receptor for the N-terminus of Nogo- B, a neural and cardiovascular regulator. Regulates the stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 | 0.712 |
NUS1 | EPRS | ENSP00000357480 | ENSP00000355890 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae); Acts as a specific receptor for the N-terminus of Nogo- B, a neural and cardiovascular regulator. Regulates the stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol | glutamyl-prolyl-tRNA synthetase | 0.672 |
NUS1 | REEP5 | ENSP00000357480 | ENSP00000368959 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae); Acts as a specific receptor for the N-terminus of Nogo- B, a neural and cardiovascular regulator. Regulates the stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol | receptor accessory protein 5; May promote functional cell surface expression of olfactory receptors | 0.680 |
NUS1 | RTN1 | ENSP00000357480 | ENSP00000267484 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae); Acts as a specific receptor for the N-terminus of Nogo- B, a neural and cardiovascular regulator. Regulates the stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol | reticulon 1; May be involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells | 0.655 |