TCERG1L protein (Homo sapiens) - STRING network view

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TCERG1L

transcription elongation regulator 1-like (586 aa)

Predicted Functional Partners:

POLR2F

0.703

HTT

0.592

C22orf34

0.583

PPP2R2D

0.582

HTATSF1

0.518

TMEM132C

0.507

GPR151

0.482

CARM1

0.415

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C22orf34	TCERG1L	ENSP00000395549	ENSP00000357631	chromosome 22 open reading frame 34	transcription elongation regulator 1-like	0.583
C22orf34	TMEM132C	ENSP00000395549	ENSP00000410852	chromosome 22 open reading frame 34	transmembrane protein 132C	0.811
CARM1	TCERG1L	ENSP00000325690	ENSP00000357631	coactivator-associated arginine methyltransferase 1; Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at ’Arg-17’ (H3R17me), forming mainly asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/ [...]	transcription elongation regulator 1-like	0.415
GPR151	TCERG1L	ENSP00000308733	ENSP00000357631	G protein-coupled receptor 151; Orphan receptor	transcription elongation regulator 1-like	0.482
HTATSF1	TCERG1L	ENSP00000218364	ENSP00000357631	HIV-1 Tat specific factor 1; Functions as a general transcription factor playing a role in the process of transcriptional elongation. May mediate the reciprocal stimulatory effect of splicing on transcriptional elongation. In case of infection by HIV-1, it is up-regulated by the HIV-1 proteins NEF and gp120, acts as a cofactor required for the Tat-enhanced transcription of the virus	transcription elongation regulator 1-like	0.518
HTT	TCERG1L	ENSP00000347184	ENSP00000357631	huntingtin; May play a role in microtubule-mediated transport or vesicle function	transcription elongation regulator 1-like	0.592
POLR2F	TCERG1L	ENSP00000403852	ENSP00000357631	polymerase (RNA) II (DNA directed) polypeptide F; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II, and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2F/RPB6 is part of the clamp ele [...]	transcription elongation regulator 1-like	0.703
PPP2R2D	TCERG1L	ENSP00000399970	ENSP00000357631	protein phosphatase 2, regulatory subunit B, delta; B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55- delta) fluctuate during the cell cycle- the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also may direct the localization of t [...]	transcription elongation regulator 1-like	0.582
TCERG1L	C22orf34	ENSP00000357631	ENSP00000395549	transcription elongation regulator 1-like	chromosome 22 open reading frame 34	0.583
TCERG1L	CARM1	ENSP00000357631	ENSP00000325690	transcription elongation regulator 1-like	coactivator-associated arginine methyltransferase 1; Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at ’Arg-17’ (H3R17me), forming mainly asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/ [...]	0.415
TCERG1L	GPR151	ENSP00000357631	ENSP00000308733	transcription elongation regulator 1-like	G protein-coupled receptor 151; Orphan receptor	0.482
TCERG1L	HTATSF1	ENSP00000357631	ENSP00000218364	transcription elongation regulator 1-like	HIV-1 Tat specific factor 1; Functions as a general transcription factor playing a role in the process of transcriptional elongation. May mediate the reciprocal stimulatory effect of splicing on transcriptional elongation. In case of infection by HIV-1, it is up-regulated by the HIV-1 proteins NEF and gp120, acts as a cofactor required for the Tat-enhanced transcription of the virus	0.518
TCERG1L	HTT	ENSP00000357631	ENSP00000347184	transcription elongation regulator 1-like	huntingtin; May play a role in microtubule-mediated transport or vesicle function	0.592
TCERG1L	POLR2F	ENSP00000357631	ENSP00000403852	transcription elongation regulator 1-like	polymerase (RNA) II (DNA directed) polypeptide F; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II, and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2F/RPB6 is part of the clamp ele [...]	0.703
TCERG1L	PPP2R2D	ENSP00000357631	ENSP00000399970	transcription elongation regulator 1-like	protein phosphatase 2, regulatory subunit B, delta; B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55- delta) fluctuate during the cell cycle- the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also may direct the localization of t [...]	0.582
TCERG1L	TMEM132C	ENSP00000357631	ENSP00000410852	transcription elongation regulator 1-like	transmembrane protein 132C	0.507
TMEM132C	C22orf34	ENSP00000410852	ENSP00000395549	transmembrane protein 132C	chromosome 22 open reading frame 34	0.811
TMEM132C	TCERG1L	ENSP00000410852	ENSP00000357631	transmembrane protein 132C	transcription elongation regulator 1-like	0.507

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