Full Link:
  • Version:
  • 10.0 (archived version)
STRINGSTRING
KIFC3 KIFC3 KIFC1 KIFC1 CCDC88B CCDC88B CKAP5 CKAP5 TUBE1 TUBE1 TBCA TBCA KIF25 KIF25 UBC UBC TBCD TBCD KIFC2 KIFC2 TBCE TBCE
"TUBE1" - tubulin, epsilon 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TUBE1tubulin, epsilon 1 (475 aa)    
Predicted Functional Partners:
KIFC3
kinesin family member C3; Minus-end microtubule-dependent motor protein. Involved in apically targeted transport (By similarity). Required for zonula adherens maintenance (833 aa)
        score_image   score_image   0.658
CKAP5
cytoskeleton associated protein 5; Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle poles (2032 aa)
        score_image   score_image   0.653
TBCA
tubulin folding cofactor A; Tubulin-folding protein; involved in the early step of the tubulin folding pathway (108 aa)
        score_image   score_image   0.645
UBC
ubiquitin C (685 aa)
        score_image   score_image   0.637
TBCE
tubulin folding cofactor E; Tubulin-folding protein; involved in the second step of the tubulin folding pathway. Seems to be implicated in the maintenance of the neuronal microtubule network. Involved in regulation of tubulin heterodimer dissociation (527 aa)
        score_image   score_image   0.634
CCDC88B
coiled-coil domain containing 88B (1476 aa)
        score_image   score_image   0.628
TBCD
tubulin folding cofactor D (1192 aa)
        score_image   score_image   0.623
KIFC1
kinesin family member C1 (673 aa)
        score_image   score_image   0.616
KIF25
kinesin family member 25; Negative regulator of amino acid starvation-induced autophagy (384 aa)
        score_image   score_image   0.616
KIFC2
kinesin family member C2; May play a role in microtubule-dependent retrograde axonal transport. May function as the motor for the transport of multivesicular body (MVB)-like organelles in dendrites (By similarity) (838 aa)
        score_image   score_image   0.616
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Server load: low (39%)