node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKRD46 | FANK1 | ENSP00000335287 | ENSP00000357682 | ankyrin repeat domain 46 | fibronectin type III and ankyrin repeat domains 1 | 0.451 |
C16orf80 | FANK1 | ENSP00000262498 | ENSP00000357682 | chromosome 16 open reading frame 80 | fibronectin type III and ankyrin repeat domains 1 | 0.489 |
CDK17 | FANK1 | ENSP00000261211 | ENSP00000357682 | cyclin-dependent kinase 17; May play a role in terminally differentiated neurons. Has a Ser/Thr-phosphorylating activity for histone H1 (By similarity) | fibronectin type III and ankyrin repeat domains 1 | 0.443 |
CDK18 | FANK1 | ENSP00000423665 | ENSP00000357682 | cyclin-dependent kinase 18; May play a role in signal transduction cascades in terminally differentiated cells | fibronectin type III and ankyrin repeat domains 1 | 0.440 |
COPS5 | FANK1 | ENSP00000350512 | ENSP00000357682 | COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis); Probable protease subunit of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8, possibly via i [...] | fibronectin type III and ankyrin repeat domains 1 | 0.922 |
FANK1 | ANKRD46 | ENSP00000357682 | ENSP00000335287 | fibronectin type III and ankyrin repeat domains 1 | ankyrin repeat domain 46 | 0.451 |
FANK1 | C16orf80 | ENSP00000357682 | ENSP00000262498 | fibronectin type III and ankyrin repeat domains 1 | chromosome 16 open reading frame 80 | 0.489 |
FANK1 | CDK17 | ENSP00000357682 | ENSP00000261211 | fibronectin type III and ankyrin repeat domains 1 | cyclin-dependent kinase 17; May play a role in terminally differentiated neurons. Has a Ser/Thr-phosphorylating activity for histone H1 (By similarity) | 0.443 |
FANK1 | CDK18 | ENSP00000357682 | ENSP00000423665 | fibronectin type III and ankyrin repeat domains 1 | cyclin-dependent kinase 18; May play a role in signal transduction cascades in terminally differentiated cells | 0.440 |
FANK1 | COPS5 | ENSP00000357682 | ENSP00000350512 | fibronectin type III and ankyrin repeat domains 1 | COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis); Probable protease subunit of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8, possibly via i [...] | 0.922 |
FANK1 | GZF1 | ENSP00000357682 | ENSP00000338290 | fibronectin type III and ankyrin repeat domains 1 | GDNF-inducible zinc finger protein 1 | 0.651 |
FANK1 | NEURL | ENSP00000357682 | ENSP00000358795 | fibronectin type III and ankyrin repeat domains 1 | neuralized homolog (Drosophila); May function as an E3 ubiquitin-protein ligase to activate monoubiquitination of JAG1, thereby regulating the Notch pathway (By similarity) | 0.585 |
FANK1 | NEURL1B | ENSP00000357682 | ENSP00000358815 | fibronectin type III and ankyrin repeat domains 1 | neuralized homolog 1B (Drosophila); E3 ubiquitin-protein ligase involved in regulation of the Notch pathway through influencing the stability and activity of several Notch ligands | 0.585 |
FANK1 | PWP1 | ENSP00000357682 | ENSP00000387365 | fibronectin type III and ankyrin repeat domains 1 | PWP1 homolog (S. cerevisiae); May play an important role in cell growth and/or transcription | 0.524 |
FANK1 | SPATA4 | ENSP00000357682 | ENSP00000280191 | fibronectin type III and ankyrin repeat domains 1 | spermatogenesis associated 4 | 0.688 |
GZF1 | FANK1 | ENSP00000338290 | ENSP00000357682 | GDNF-inducible zinc finger protein 1 | fibronectin type III and ankyrin repeat domains 1 | 0.651 |
NEURL | FANK1 | ENSP00000358795 | ENSP00000357682 | neuralized homolog (Drosophila); May function as an E3 ubiquitin-protein ligase to activate monoubiquitination of JAG1, thereby regulating the Notch pathway (By similarity) | fibronectin type III and ankyrin repeat domains 1 | 0.585 |
NEURL1B | FANK1 | ENSP00000358815 | ENSP00000357682 | neuralized homolog 1B (Drosophila); E3 ubiquitin-protein ligase involved in regulation of the Notch pathway through influencing the stability and activity of several Notch ligands | fibronectin type III and ankyrin repeat domains 1 | 0.585 |
PWP1 | FANK1 | ENSP00000387365 | ENSP00000357682 | PWP1 homolog (S. cerevisiae); May play an important role in cell growth and/or transcription | fibronectin type III and ankyrin repeat domains 1 | 0.524 |
SPATA4 | FANK1 | ENSP00000280191 | ENSP00000357682 | spermatogenesis associated 4 | fibronectin type III and ankyrin repeat domains 1 | 0.688 |