node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C1orf68 | LCE2A | ENSP00000354769 | ENSP00000357768 | chromosome 1 open reading frame 68 | late cornified envelope 2A; Precursors of the cornified envelope of the stratum corneum | 0.539 |
C1orf68 | LCE3A | ENSP00000354769 | ENSP00000335006 | chromosome 1 open reading frame 68 | late cornified envelope 3A; Precursors of the cornified envelope of the stratum corneum | 0.407 |
C1orf68 | LCE3D | ENSP00000354769 | ENSP00000357776 | chromosome 1 open reading frame 68 | late cornified envelope 3D; Precursors of the cornified envelope of the stratum corneum | 0.471 |
C1orf68 | LCE4A | ENSP00000354769 | ENSP00000335223 | chromosome 1 open reading frame 68 | late cornified envelope 4A; Precursors of the cornified envelope of the stratum corneum | 0.561 |
ELOVL6 | LCE1E | ENSP00000304736 | ENSP00000357759 | ELOVL fatty acid elongase 6; Condensing enzyme that catalyzes the synthesis of saturated and monounsaturated fatty acids. Highest activity toward C16-0 acyl-CoAs | late cornified envelope 1E; Precursors of the cornified envelope of the stratum corneum | 0.748 |
ELOVL6 | LCE2A | ENSP00000304736 | ENSP00000357768 | ELOVL fatty acid elongase 6; Condensing enzyme that catalyzes the synthesis of saturated and monounsaturated fatty acids. Highest activity toward C16-0 acyl-CoAs | late cornified envelope 2A; Precursors of the cornified envelope of the stratum corneum | 0.750 |
ELOVL6 | LCE3A | ENSP00000304736 | ENSP00000335006 | ELOVL fatty acid elongase 6; Condensing enzyme that catalyzes the synthesis of saturated and monounsaturated fatty acids. Highest activity toward C16-0 acyl-CoAs | late cornified envelope 3A; Precursors of the cornified envelope of the stratum corneum | 0.750 |
ELOVL6 | LCE3D | ENSP00000304736 | ENSP00000357776 | ELOVL fatty acid elongase 6; Condensing enzyme that catalyzes the synthesis of saturated and monounsaturated fatty acids. Highest activity toward C16-0 acyl-CoAs | late cornified envelope 3D; Precursors of the cornified envelope of the stratum corneum | 0.757 |
ELOVL6 | LCE4A | ENSP00000304736 | ENSP00000335223 | ELOVL fatty acid elongase 6; Condensing enzyme that catalyzes the synthesis of saturated and monounsaturated fatty acids. Highest activity toward C16-0 acyl-CoAs | late cornified envelope 4A; Precursors of the cornified envelope of the stratum corneum | 0.681 |
KRTAP4-2 | LCE2A | ENSP00000366955 | ENSP00000357768 | keratin associated protein 4-2; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins | late cornified envelope 2A; Precursors of the cornified envelope of the stratum corneum | 0.531 |
LCE1E | ELOVL6 | ENSP00000357759 | ENSP00000304736 | late cornified envelope 1E; Precursors of the cornified envelope of the stratum corneum | ELOVL fatty acid elongase 6; Condensing enzyme that catalyzes the synthesis of saturated and monounsaturated fatty acids. Highest activity toward C16-0 acyl-CoAs | 0.748 |
LCE1E | LCE2A | ENSP00000357759 | ENSP00000357768 | late cornified envelope 1E; Precursors of the cornified envelope of the stratum corneum | late cornified envelope 2A; Precursors of the cornified envelope of the stratum corneum | 0.583 |
LCE1E | LCE4A | ENSP00000357759 | ENSP00000335223 | late cornified envelope 1E; Precursors of the cornified envelope of the stratum corneum | late cornified envelope 4A; Precursors of the cornified envelope of the stratum corneum | 0.561 |
LCE2A | C1orf68 | ENSP00000357768 | ENSP00000354769 | late cornified envelope 2A; Precursors of the cornified envelope of the stratum corneum | chromosome 1 open reading frame 68 | 0.539 |
LCE2A | ELOVL6 | ENSP00000357768 | ENSP00000304736 | late cornified envelope 2A; Precursors of the cornified envelope of the stratum corneum | ELOVL fatty acid elongase 6; Condensing enzyme that catalyzes the synthesis of saturated and monounsaturated fatty acids. Highest activity toward C16-0 acyl-CoAs | 0.750 |
LCE2A | KRTAP4-2 | ENSP00000357768 | ENSP00000366955 | late cornified envelope 2A; Precursors of the cornified envelope of the stratum corneum | keratin associated protein 4-2; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins | 0.531 |
LCE2A | LCE1E | ENSP00000357768 | ENSP00000357759 | late cornified envelope 2A; Precursors of the cornified envelope of the stratum corneum | late cornified envelope 1E; Precursors of the cornified envelope of the stratum corneum | 0.583 |
LCE2A | LCE3A | ENSP00000357768 | ENSP00000335006 | late cornified envelope 2A; Precursors of the cornified envelope of the stratum corneum | late cornified envelope 3A; Precursors of the cornified envelope of the stratum corneum | 0.509 |
LCE2A | LCE3D | ENSP00000357768 | ENSP00000357776 | late cornified envelope 2A; Precursors of the cornified envelope of the stratum corneum | late cornified envelope 3D; Precursors of the cornified envelope of the stratum corneum | 0.507 |
LCE2A | LCE4A | ENSP00000357768 | ENSP00000335223 | late cornified envelope 2A; Precursors of the cornified envelope of the stratum corneum | late cornified envelope 4A; Precursors of the cornified envelope of the stratum corneum | 0.725 |