node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKRD18A | LCE2D | ENSP00000382610 | ENSP00000357773 | ankyrin repeat domain 18A | late cornified envelope 2D; Precursors of the cornified envelope of the stratum corneum | 0.418 |
ANKRD18B | LCE2D | ENSP00000290943 | ENSP00000357773 | ankyrin repeat domain 18B | late cornified envelope 2D; Precursors of the cornified envelope of the stratum corneum | 0.475 |
ELOVL6 | LCE2C | ENSP00000304736 | ENSP00000357772 | ELOVL fatty acid elongase 6; Condensing enzyme that catalyzes the synthesis of saturated and monounsaturated fatty acids. Highest activity toward C16-0 acyl-CoAs | late cornified envelope 2C; Precursors of the cornified envelope of the stratum | 0.750 |
ELOVL6 | LCE2D | ENSP00000304736 | ENSP00000357773 | ELOVL fatty acid elongase 6; Condensing enzyme that catalyzes the synthesis of saturated and monounsaturated fatty acids. Highest activity toward C16-0 acyl-CoAs | late cornified envelope 2D; Precursors of the cornified envelope of the stratum corneum | 0.750 |
ELOVL6 | LCE3A | ENSP00000304736 | ENSP00000335006 | ELOVL fatty acid elongase 6; Condensing enzyme that catalyzes the synthesis of saturated and monounsaturated fatty acids. Highest activity toward C16-0 acyl-CoAs | late cornified envelope 3A; Precursors of the cornified envelope of the stratum corneum | 0.750 |
ELOVL6 | LCE3C | ENSP00000304736 | ENSP00000334644 | ELOVL fatty acid elongase 6; Condensing enzyme that catalyzes the synthesis of saturated and monounsaturated fatty acids. Highest activity toward C16-0 acyl-CoAs | late cornified envelope 3C; Precursors of the cornified envelope of the stratum corneum | 0.800 |
ELOVL6 | LCE3D | ENSP00000304736 | ENSP00000357776 | ELOVL fatty acid elongase 6; Condensing enzyme that catalyzes the synthesis of saturated and monounsaturated fatty acids. Highest activity toward C16-0 acyl-CoAs | late cornified envelope 3D; Precursors of the cornified envelope of the stratum corneum | 0.757 |
GLRX3 | LCE2D | ENSP00000330836 | ENSP00000357773 | glutaredoxin 3; Critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity). May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity | late cornified envelope 2D; Precursors of the cornified envelope of the stratum corneum | 0.503 |
LCE2C | ELOVL6 | ENSP00000357772 | ENSP00000304736 | late cornified envelope 2C; Precursors of the cornified envelope of the stratum | ELOVL fatty acid elongase 6; Condensing enzyme that catalyzes the synthesis of saturated and monounsaturated fatty acids. Highest activity toward C16-0 acyl-CoAs | 0.750 |
LCE2C | LCE2D | ENSP00000357772 | ENSP00000357773 | late cornified envelope 2C; Precursors of the cornified envelope of the stratum | late cornified envelope 2D; Precursors of the cornified envelope of the stratum corneum | 0.588 |
LCE2C | LCE3D | ENSP00000357772 | ENSP00000357776 | late cornified envelope 2C; Precursors of the cornified envelope of the stratum | late cornified envelope 3D; Precursors of the cornified envelope of the stratum corneum | 0.501 |
LCE2D | ANKRD18A | ENSP00000357773 | ENSP00000382610 | late cornified envelope 2D; Precursors of the cornified envelope of the stratum corneum | ankyrin repeat domain 18A | 0.418 |
LCE2D | ANKRD18B | ENSP00000357773 | ENSP00000290943 | late cornified envelope 2D; Precursors of the cornified envelope of the stratum corneum | ankyrin repeat domain 18B | 0.475 |
LCE2D | ELOVL6 | ENSP00000357773 | ENSP00000304736 | late cornified envelope 2D; Precursors of the cornified envelope of the stratum corneum | ELOVL fatty acid elongase 6; Condensing enzyme that catalyzes the synthesis of saturated and monounsaturated fatty acids. Highest activity toward C16-0 acyl-CoAs | 0.750 |
LCE2D | GLRX3 | ENSP00000357773 | ENSP00000330836 | late cornified envelope 2D; Precursors of the cornified envelope of the stratum corneum | glutaredoxin 3; Critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity). May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity | 0.503 |
LCE2D | LCE2C | ENSP00000357773 | ENSP00000357772 | late cornified envelope 2D; Precursors of the cornified envelope of the stratum corneum | late cornified envelope 2C; Precursors of the cornified envelope of the stratum | 0.588 |
LCE2D | LCE3A | ENSP00000357773 | ENSP00000335006 | late cornified envelope 2D; Precursors of the cornified envelope of the stratum corneum | late cornified envelope 3A; Precursors of the cornified envelope of the stratum corneum | 0.508 |
LCE2D | LCE3C | ENSP00000357773 | ENSP00000334644 | late cornified envelope 2D; Precursors of the cornified envelope of the stratum corneum | late cornified envelope 3C; Precursors of the cornified envelope of the stratum corneum | 0.472 |
LCE2D | LCE3D | ENSP00000357773 | ENSP00000357776 | late cornified envelope 2D; Precursors of the cornified envelope of the stratum corneum | late cornified envelope 3D; Precursors of the cornified envelope of the stratum corneum | 0.506 |
LCE2D | MAGEA11 | ENSP00000357773 | ENSP00000347358 | late cornified envelope 2D; Precursors of the cornified envelope of the stratum corneum | melanoma antigen family A, 11; Acts as androgen receptor co-regulator that increases androgen receptor activity by modulating the receptors interdomain interaction. May play a role in embryonal development and tumor transformation or aspects of tumor progression | 0.505 |