Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
|
Your Input:
|
Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
|||||
 | CRCT1 | cysteine-rich C-terminal 1 (99 aa) | ||||||||||||
Predicted Functional Partners:
| ||||||||||||||
 | UBAP2L | ubiquitin associated protein 2-like (1087 aa) |
 |
0.720 | ||||||||||
 | C1orf43 | chromosome 1 open reading frame 43 (253 aa) |
|
0.582 | ||||||||||
 | LCE6A | late cornified envelope 6A; Precursors of the cornified envelope of the stratum corneum (By similarity) (80 aa) |
|
0.567 | ||||||||||
 | KPRP | keratinocyte proline-rich protein (579 aa) |
|
0.533 | ||||||||||
 | LCE3E | late cornified envelope 3E; Precursors of the cornified envelope of the stratum corneum (92 aa) |
|
0.513 | ||||||||||
 | C8orf58 | chromosome 8 open reading frame 58 (365 aa) |
|
0.472 | ||||||||||
 | S100A7A | S100 calcium binding protein A7A; May be involved in epidermal differentiation and inflammation and might therefore be important for the pathogenesis of psoriasis and other diseases (101 aa) |
|
0.470 | ||||||||||
 | KIAA1614 | KIAA1614 (1190 aa) |
|
0.418 | ||||||||||
 | GOLGA6L9 | golgin A6 family-like 9 (432 aa) |
|
0.418 | ||||||||||
 | LCE3D | late cornified envelope 3D; Precursors of the cornified envelope of the stratum corneum (92 aa) |
|
0.414 | ||||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
Share
