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STRINGSTRING
LELP1 LELP1 OTUD4 OTUD4 UBC UBC HRNR HRNR IVL IVL LOR LOR RAD51C RAD51C LCE5A LCE5A
"HRNR" - hornerin in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HRNRhornerin; May play a role in cornification (2850 aa)    
Predicted Functional Partners:
OTUD4
OTU domain containing 4 (1049 aa)
        score_image       0.740
LCE5A
late cornified envelope 5A; Precursors of the cornified envelope of the stratum corneum (118 aa)
            score_image   0.537
UBC
ubiquitin C (685 aa)
        score_image   score_image   0.523
LOR
loricrin; Major keratinocyte cell envelope protein (312 aa)
            score_image   0.504
LELP1
late cornified envelope-like proline-rich 1 (98 aa)
            score_image   0.475
RAD51C
RAD51 homolog C (S. cerevisiae); Essential for the homologous recombination (HR) pathway of DNA repair. Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. The RAD51B-RAD51C dimer exhibits single-stranded DNA-dependent ATPase activity. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Participates in branch migration and Holliday junction resolution and thus is important for processing HR intermediates late in t [...] (376 aa)
        score_image       0.469
IVL
involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia (By similarity) (585 aa)
            score_image   0.461
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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