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STRINGSTRING
UBC UBC ALDH18A1 ALDH18A1 ALDH4A1 ALDH4A1 ASS1 ASS1 ODC1 ODC1 OAT OAT ARG1 ARG1 NAGS NAGS OTC OTC ARG2 ARG2 ENSG00000114786 ENSG00000114786
"OAT" - ornithine aminotransferase in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
OATornithine aminotransferase (439 aa)    
Predicted Functional Partners:
OTC
ornithine carbamoyltransferase (354 aa)
score_image score_image   score_image   score_image score_image   0.993
ALDH18A1
aldehyde dehydrogenase 18 family, member A1 (795 aa)
score_image     score_image score_image   score_image   0.991
ARG2
arginase, type II; May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders (354 aa)
score_image     score_image   score_image score_image   0.986
ARG1
arginase, liver (322 aa)
score_image     score_image   score_image score_image   0.982
ALDH4A1
aldehyde dehydrogenase 4 family, member A1 (563 aa)
score_image   score_image score_image   score_image score_image   0.969
ODC1
ornithine decarboxylase 1 (461 aa)
score_image         score_image score_image   0.962
ENSG00000114786
ABHD14A-ACY1 readthrough (non-protein coding) (509 aa)
score_image         score_image score_image   0.946
UBC
ubiquitin C (685 aa)
        score_image   score_image   0.932
ASS1
argininosuccinate synthase 1; Is indirectly involved in the control of blood pressure (By similarity) (412 aa)
score_image     score_image     score_image   0.876
NAGS
N-acetylglutamate synthase; Plays a role in the regulation of ureagenesis by producing variable amounts of N-acetylglutamate (NAG), thus modulating carbamoylphosphate synthase I (CPSI) activity (534 aa)
score_image     score_image     score_image   0.856
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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