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STRINGSTRING
SLC6A19 SLC6A19 SLC47A1 SLC47A1 SLC22A16 SLC22A16 SLC26A6 SLC26A6 CBR3 CBR3
"SLC22A16" - solute carrier family 22 (organic cation/carnitine transporter), member 16 in Homo sapiens
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protein of unknown 3D structure
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SLC22A16solute carrier family 22 (organic cation/carnitine transporter), member 16; High affinity carnitine transporter; the uptake is partially sodium-ion dependent. Thought to mediate the L-carnitine secretion mechanism from testis epididymal epithelium into the lumen which is involved in the maturation of spermatozoa. Also transports organic cations such as tetraethylammonium (TEA) and doxorubicin. The uptake of TEA is inhibited by various organic cations. The uptake of doxorubicin is sodium-independent (577 aa)    
Predicted Functional Partners:
SLC26A6
solute carrier family 26, member 6; Does not seem to be involved in anion transport (759 aa)
            score_image   0.532
SLC47A1
solute carrier family 47, member 1; Solute transporter for tetraethylammonium (TEA), 1- methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, ganciclovir and also the zwitterionic cephalosporin, cephalexin and cephradin. Seems to also play a role in the uptake of oxaliplatin (a new platinum anticancer agent). Able to transport paraquat (PQ or N,N-dimethyl-4-4’-bipiridinium); a widely used herbicid. Responsible for the secretion of cationic drugs across the brush border membranes (570 aa)
            score_image   0.527
CBR3
carbonyl reductase 3; Has low NADPH-dependent oxidoreductase activity towards 4-benzoylpyridine and menadione (in vitro) (277 aa)
            score_image   0.446
SLC6A19
solute carrier family 6 (neutral amino acid transporter), member 19; Transporter that mediates epithelial resorption of neutral amino acids across the apical membrane of epithelial cells in the kidney and intestine. It appears that leucine is the preferred substrate, but all large neutral non-aromatic L-amino acids bind to this transporter. Uptake of leucine is sodium- dependent. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent (By similarity) (634 aa)
            score_image   0.415
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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