SCML4 protein (Homo sapiens) - STRING network view

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protein of unknown 3D structure

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SCML4

sex comb on midleg-like 4 (Drosophila); Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity) (414 aa)

Predicted Functional Partners:

ODF3B

0.625

TMEM117

0.501

SFTA3

0.499

MBTD1

0.489

SPATS1

0.457

TMED3

0.445

ODF3

0.420

TMEM87A

0.416

DHRS7

0.405

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DHRS7	ODF3B	ENSP00000216500	ENSP00000382804	dehydrogenase/reductase (SDR family) member 7	outer dense fiber of sperm tails 3B	0.560
DHRS7	SCML4	ENSP00000216500	ENSP00000358016	dehydrogenase/reductase (SDR family) member 7	sex comb on midleg-like 4 (Drosophila); Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity)	0.405
MBTD1	SCML4	ENSP00000403946	ENSP00000358016	mbt domain containing 1; Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility (By similarity). Specifically binds to monomethylated and dimethylated ’Lys-20’ on histone H4	sex comb on midleg-like 4 (Drosophila); Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity)	0.489
ODF3	SCML4	ENSP00000325868	ENSP00000358016	outer dense fiber of sperm tails 3; Outer dense fibers are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail. May help to maintain the passive elastic structures and elastic recoil of the sperm tail	sex comb on midleg-like 4 (Drosophila); Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity)	0.420
ODF3B	DHRS7	ENSP00000382804	ENSP00000216500	outer dense fiber of sperm tails 3B	dehydrogenase/reductase (SDR family) member 7	0.560
ODF3B	SCML4	ENSP00000382804	ENSP00000358016	outer dense fiber of sperm tails 3B	sex comb on midleg-like 4 (Drosophila); Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity)	0.625
SCML4	DHRS7	ENSP00000358016	ENSP00000216500	sex comb on midleg-like 4 (Drosophila); Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity)	dehydrogenase/reductase (SDR family) member 7	0.405
SCML4	MBTD1	ENSP00000358016	ENSP00000403946	sex comb on midleg-like 4 (Drosophila); Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity)	mbt domain containing 1; Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility (By similarity). Specifically binds to monomethylated and dimethylated ’Lys-20’ on histone H4	0.489
SCML4	ODF3	ENSP00000358016	ENSP00000325868	sex comb on midleg-like 4 (Drosophila); Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity)	outer dense fiber of sperm tails 3; Outer dense fibers are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail. May help to maintain the passive elastic structures and elastic recoil of the sperm tail	0.420
SCML4	ODF3B	ENSP00000358016	ENSP00000382804	sex comb on midleg-like 4 (Drosophila); Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity)	outer dense fiber of sperm tails 3B	0.625
SCML4	SFTA3	ENSP00000358016	ENSP00000428331	sex comb on midleg-like 4 (Drosophila); Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity)	surfactant associated 3	0.499
SCML4	SPATS1	ENSP00000358016	ENSP00000424400	sex comb on midleg-like 4 (Drosophila); Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity)	spermatogenesis associated, serine-rich 1	0.457
SCML4	TMED3	ENSP00000358016	ENSP00000299705	sex comb on midleg-like 4 (Drosophila); Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity)	transmembrane emp24 protein transport domain containing 3; Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network	0.445
SCML4	TMEM117	ENSP00000358016	ENSP00000266534	sex comb on midleg-like 4 (Drosophila); Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity)	transmembrane protein 117	0.501
SCML4	TMEM87A	ENSP00000358016	ENSP00000374484	sex comb on midleg-like 4 (Drosophila); Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity)	transmembrane protein 87A	0.416
SFTA3	SCML4	ENSP00000428331	ENSP00000358016	surfactant associated 3	sex comb on midleg-like 4 (Drosophila); Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity)	0.499
SFTA3	TMEM117	ENSP00000428331	ENSP00000266534	surfactant associated 3	transmembrane protein 117	0.501
SFTA3	TMEM87A	ENSP00000428331	ENSP00000374484	surfactant associated 3	transmembrane protein 87A	0.416
SPATS1	SCML4	ENSP00000424400	ENSP00000358016	spermatogenesis associated, serine-rich 1	sex comb on midleg-like 4 (Drosophila); Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity)	0.457
TMED3	SCML4	ENSP00000299705	ENSP00000358016	transmembrane emp24 protein transport domain containing 3; Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network	sex comb on midleg-like 4 (Drosophila); Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity)	0.445

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