| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATRNL1 | FAM160B1 | ENSP00000347152 | ENSP00000358251 | attractin-like 1; May play a role in melanocortin signaling pathways that regulate energy homeostasis (By similarity) | family with sequence similarity 160, member B1 | 0.577 |
| CACUL1 | CECR2 | ENSP00000358147 | ENSP00000262608 | CDK2-associated, cullin domain 1; Cell cycle associated protein capable of promoting cell proliferation through the activation of CDK2 at the G1/S phase transition | cat eye syndrome chromosome region, candidate 2; Part of the CERF (CECR2-containing-remodeling factor) complex, which facilitates the perturbation of chromatin structure in an ATP-dependent manner. May be involved through its interaction with LRPPRC in the integration of cytoskeletal network with vesicular trafficking, nucleocytosolic shuttling, transcription, chromosome remodeling and cytokinesis | 0.420 |
| CACUL1 | FAM160B1 | ENSP00000358147 | ENSP00000358251 | CDK2-associated, cullin domain 1; Cell cycle associated protein capable of promoting cell proliferation through the activation of CDK2 at the G1/S phase transition | family with sequence similarity 160, member B1 | 0.487 |
| CACUL1 | FAM204A | ENSP00000358147 | ENSP00000358170 | CDK2-associated, cullin domain 1; Cell cycle associated protein capable of promoting cell proliferation through the activation of CDK2 at the G1/S phase transition | family with sequence similarity 204, member A | 0.592 |
| CACUL1 | UBC | ENSP00000358147 | ENSP00000344818 | CDK2-associated, cullin domain 1; Cell cycle associated protein capable of promoting cell proliferation through the activation of CDK2 at the G1/S phase transition | ubiquitin C | 0.701 |
| CECR2 | CACUL1 | ENSP00000262608 | ENSP00000358147 | cat eye syndrome chromosome region, candidate 2; Part of the CERF (CECR2-containing-remodeling factor) complex, which facilitates the perturbation of chromatin structure in an ATP-dependent manner. May be involved through its interaction with LRPPRC in the integration of cytoskeletal network with vesicular trafficking, nucleocytosolic shuttling, transcription, chromosome remodeling and cytokinesis | CDK2-associated, cullin domain 1; Cell cycle associated protein capable of promoting cell proliferation through the activation of CDK2 at the G1/S phase transition | 0.420 |
| CECR2 | EXOSC1 | ENSP00000262608 | ENSP00000359939 | cat eye syndrome chromosome region, candidate 2; Part of the CERF (CECR2-containing-remodeling factor) complex, which facilitates the perturbation of chromatin structure in an ATP-dependent manner. May be involved through its interaction with LRPPRC in the integration of cytoskeletal network with vesicular trafficking, nucleocytosolic shuttling, transcription, chromosome remodeling and cytokinesis | exosome component 1; Non-catalytic component of the RNA exosome complex which has 3’->5’ exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding ’pervasive’ transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The R [...] | 0.598 |
| CECR2 | FAM160B1 | ENSP00000262608 | ENSP00000358251 | cat eye syndrome chromosome region, candidate 2; Part of the CERF (CECR2-containing-remodeling factor) complex, which facilitates the perturbation of chromatin structure in an ATP-dependent manner. May be involved through its interaction with LRPPRC in the integration of cytoskeletal network with vesicular trafficking, nucleocytosolic shuttling, transcription, chromosome remodeling and cytokinesis | family with sequence similarity 160, member B1 | 0.639 |
| CECR2 | TRIT1 | ENSP00000262608 | ENSP00000321810 | cat eye syndrome chromosome region, candidate 2; Part of the CERF (CECR2-containing-remodeling factor) complex, which facilitates the perturbation of chromatin structure in an ATP-dependent manner. May be involved through its interaction with LRPPRC in the integration of cytoskeletal network with vesicular trafficking, nucleocytosolic shuttling, transcription, chromosome remodeling and cytokinesis | tRNA isopentenyltransferase 1; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 of both cytosolic and mitochondrial tRNAs, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) | 0.492 |
| CECR2 | UBC | ENSP00000262608 | ENSP00000344818 | cat eye syndrome chromosome region, candidate 2; Part of the CERF (CECR2-containing-remodeling factor) complex, which facilitates the perturbation of chromatin structure in an ATP-dependent manner. May be involved through its interaction with LRPPRC in the integration of cytoskeletal network with vesicular trafficking, nucleocytosolic shuttling, transcription, chromosome remodeling and cytokinesis | ubiquitin C | 0.464 |
| DENND6A | FAM160B1 | ENSP00000311401 | ENSP00000358251 | DENN/MADD domain containing 6A; Guanine nucleotide exchange factor (GEF) for RAB14. Component of an endocytic recycling pathway that is required for the control of ADAM10 transport, shedding of N-cadherin/CDH2 by ADAM9 or ADAM10 and regulation of cell-cell junctions. Required for RAB14 recruitment to recycling endosomes | family with sequence similarity 160, member B1 | 0.435 |
| DENND6A | ZNF280B | ENSP00000311401 | ENSP00000353586 | DENN/MADD domain containing 6A; Guanine nucleotide exchange factor (GEF) for RAB14. Component of an endocytic recycling pathway that is required for the control of ADAM10 transport, shedding of N-cadherin/CDH2 by ADAM9 or ADAM10 and regulation of cell-cell junctions. Required for RAB14 recruitment to recycling endosomes | zinc finger protein 280B; May function as a transcription factor | 0.412 |
| EXOSC1 | CECR2 | ENSP00000359939 | ENSP00000262608 | exosome component 1; Non-catalytic component of the RNA exosome complex which has 3’->5’ exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding ’pervasive’ transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The R [...] | cat eye syndrome chromosome region, candidate 2; Part of the CERF (CECR2-containing-remodeling factor) complex, which facilitates the perturbation of chromatin structure in an ATP-dependent manner. May be involved through its interaction with LRPPRC in the integration of cytoskeletal network with vesicular trafficking, nucleocytosolic shuttling, transcription, chromosome remodeling and cytokinesis | 0.598 |
| EXOSC1 | FAM160B1 | ENSP00000359939 | ENSP00000358251 | exosome component 1; Non-catalytic component of the RNA exosome complex which has 3’->5’ exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding ’pervasive’ transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The R [...] | family with sequence similarity 160, member B1 | 0.626 |
| EXOSC1 | TRIT1 | ENSP00000359939 | ENSP00000321810 | exosome component 1; Non-catalytic component of the RNA exosome complex which has 3’->5’ exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding ’pervasive’ transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The R [...] | tRNA isopentenyltransferase 1; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 of both cytosolic and mitochondrial tRNAs, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) | 0.530 |
| EXOSC1 | UBC | ENSP00000359939 | ENSP00000344818 | exosome component 1; Non-catalytic component of the RNA exosome complex which has 3’->5’ exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding ’pervasive’ transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The R [...] | ubiquitin C | 0.723 |
| FAM160B1 | ATRNL1 | ENSP00000358251 | ENSP00000347152 | family with sequence similarity 160, member B1 | attractin-like 1; May play a role in melanocortin signaling pathways that regulate energy homeostasis (By similarity) | 0.577 |
| FAM160B1 | CACUL1 | ENSP00000358251 | ENSP00000358147 | family with sequence similarity 160, member B1 | CDK2-associated, cullin domain 1; Cell cycle associated protein capable of promoting cell proliferation through the activation of CDK2 at the G1/S phase transition | 0.487 |
| FAM160B1 | CECR2 | ENSP00000358251 | ENSP00000262608 | family with sequence similarity 160, member B1 | cat eye syndrome chromosome region, candidate 2; Part of the CERF (CECR2-containing-remodeling factor) complex, which facilitates the perturbation of chromatin structure in an ATP-dependent manner. May be involved through its interaction with LRPPRC in the integration of cytoskeletal network with vesicular trafficking, nucleocytosolic shuttling, transcription, chromosome remodeling and cytokinesis | 0.639 |
| FAM160B1 | DENND6A | ENSP00000358251 | ENSP00000311401 | family with sequence similarity 160, member B1 | DENN/MADD domain containing 6A; Guanine nucleotide exchange factor (GEF) for RAB14. Component of an endocytic recycling pathway that is required for the control of ADAM10 transport, shedding of N-cadherin/CDH2 by ADAM9 or ADAM10 and regulation of cell-cell junctions. Required for RAB14 recruitment to recycling endosomes | 0.435 |
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