node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GNL2 | GTPBP4 | ENSP00000362153 | ENSP00000354040 | guanine nucleotide binding protein-like 2 (nucleolar); GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity) | GTP binding protein 4; Involved in the biogenesis of the 60S ribosomal subunit (By similarity) | 0.999 |
GNL2 | MDN1 | ENSP00000362153 | ENSP00000358400 | guanine nucleotide binding protein-like 2 (nucleolar); GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity) | MDN1, midasin homolog (yeast); Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits (By similarity) | 0.966 |
GNL2 | MKI67IP | ENSP00000362153 | ENSP00000285814 | guanine nucleotide binding protein-like 2 (nucleolar); GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity) | MKI67 (FHA domain) interacting nucleolar phosphoprotein | 0.926 |
GNL2 | NLE1 | ENSP00000362153 | ENSP00000413572 | guanine nucleotide binding protein-like 2 (nucleolar); GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity) | notchless homolog 1 (Drosophila) | 0.994 |
GNL2 | PES1 | ENSP00000362153 | ENSP00000346725 | guanine nucleotide binding protein-like 2 (nucleolar); GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity) | pescadillo ribosomal biogenesis factor 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | 0.997 |
GNL2 | POLR1A | ENSP00000362153 | ENSP00000263857 | guanine nucleotide binding protein-like 2 (nucleolar); GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity) | polymerase (RNA) I polypeptide A, 194kDa; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Forms the polymerase active center together with the second largest subunit. A single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol I. A bridging helix emanates from RPA1 and crosses the cleft near the catalytic site and is thought to promote translocation of [...] | 0.469 |
GNL2 | SDAD1 | ENSP00000362153 | ENSP00000348596 | guanine nucleotide binding protein-like 2 (nucleolar); GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity) | SDA1 domain containing 1; Required for 60S pre-ribosomal subunits export to the cytoplasm (By similarity) | 0.985 |
GNL2 | TEX10 | ENSP00000362153 | ENSP00000364037 | guanine nucleotide binding protein-like 2 (nucleolar); GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity) | testis expressed 10; Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes | 0.967 |
GNL2 | UBC | ENSP00000362153 | ENSP00000344818 | guanine nucleotide binding protein-like 2 (nucleolar); GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity) | ubiquitin C | 0.776 |
GTPBP4 | GNL2 | ENSP00000354040 | ENSP00000362153 | GTP binding protein 4; Involved in the biogenesis of the 60S ribosomal subunit (By similarity) | guanine nucleotide binding protein-like 2 (nucleolar); GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity) | 0.999 |
GTPBP4 | MDN1 | ENSP00000354040 | ENSP00000358400 | GTP binding protein 4; Involved in the biogenesis of the 60S ribosomal subunit (By similarity) | MDN1, midasin homolog (yeast); Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits (By similarity) | 0.916 |
GTPBP4 | MKI67IP | ENSP00000354040 | ENSP00000285814 | GTP binding protein 4; Involved in the biogenesis of the 60S ribosomal subunit (By similarity) | MKI67 (FHA domain) interacting nucleolar phosphoprotein | 0.992 |
GTPBP4 | NLE1 | ENSP00000354040 | ENSP00000413572 | GTP binding protein 4; Involved in the biogenesis of the 60S ribosomal subunit (By similarity) | notchless homolog 1 (Drosophila) | 0.991 |
GTPBP4 | PES1 | ENSP00000354040 | ENSP00000346725 | GTP binding protein 4; Involved in the biogenesis of the 60S ribosomal subunit (By similarity) | pescadillo ribosomal biogenesis factor 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | 0.999 |
GTPBP4 | POLR1A | ENSP00000354040 | ENSP00000263857 | GTP binding protein 4; Involved in the biogenesis of the 60S ribosomal subunit (By similarity) | polymerase (RNA) I polypeptide A, 194kDa; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Forms the polymerase active center together with the second largest subunit. A single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol I. A bridging helix emanates from RPA1 and crosses the cleft near the catalytic site and is thought to promote translocation of [...] | 0.796 |
GTPBP4 | SDAD1 | ENSP00000354040 | ENSP00000348596 | GTP binding protein 4; Involved in the biogenesis of the 60S ribosomal subunit (By similarity) | SDA1 domain containing 1; Required for 60S pre-ribosomal subunits export to the cytoplasm (By similarity) | 0.993 |
GTPBP4 | TEX10 | ENSP00000354040 | ENSP00000364037 | GTP binding protein 4; Involved in the biogenesis of the 60S ribosomal subunit (By similarity) | testis expressed 10; Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes | 0.925 |
GTPBP4 | UBC | ENSP00000354040 | ENSP00000344818 | GTP binding protein 4; Involved in the biogenesis of the 60S ribosomal subunit (By similarity) | ubiquitin C | 0.963 |
KIAA0664 | MDN1 | ENSP00000388872 | ENSP00000358400 | KIAA0664; Involved in proper cytoplasmic distribution of mitochondria (By similarity) | MDN1, midasin homolog (yeast); Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits (By similarity) | 0.881 |
KIAA0664 | UBC | ENSP00000388872 | ENSP00000344818 | KIAA0664; Involved in proper cytoplasmic distribution of mitochondria (By similarity) | ubiquitin C | 0.956 |