ZDHHC6 protein (Homo sapiens) - STRING network view

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ZDHHC6

zinc finger, DHHC-type containing 6; Palmitoylates calnexin (CALX), which is required for its association with the ribosome-translocon complex and efficient folding of glycosylated proteins (413 aa)

Predicted Functional Partners:

AP1S3

0.655

LRRC33

0.631

GNB4

0.604

UBC

0.509

RBM23

0.505

ZDHHC12

0.485

SH3YL1

0.422

DHRS3

0.416

COL4A3BP

0.401

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP1S3	COL4A3BP	ENSP00000379891	ENSP00000369862	adaptor-related protein complex 1, sigma 3 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein	0.400
AP1S3	DHRS3	ENSP00000379891	ENSP00000365397	adaptor-related protein complex 1, sigma 3 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules	dehydrogenase/reductase (SDR family) member 3; Catalyzes the reduction of all-trans-retinal to all- trans-retinol in the presence of NADPH	0.414
AP1S3	GNB4	ENSP00000379891	ENSP00000232564	adaptor-related protein complex 1, sigma 3 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules	guanine nucleotide binding protein (G protein), beta polypeptide 4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	0.460
AP1S3	LRRC33	ENSP00000379891	ENSP00000328625	adaptor-related protein complex 1, sigma 3 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules	leucine rich repeat containing 33	0.580
AP1S3	ZDHHC6	ENSP00000379891	ENSP00000358413	adaptor-related protein complex 1, sigma 3 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules	zinc finger, DHHC-type containing 6; Palmitoylates calnexin (CALX), which is required for its association with the ribosome-translocon complex and efficient folding of glycosylated proteins	0.655
COL4A3BP	AP1S3	ENSP00000369862	ENSP00000379891	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein	adaptor-related protein complex 1, sigma 3 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules	0.400
COL4A3BP	DHRS3	ENSP00000369862	ENSP00000365397	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein	dehydrogenase/reductase (SDR family) member 3; Catalyzes the reduction of all-trans-retinal to all- trans-retinol in the presence of NADPH	0.401
COL4A3BP	UBC	ENSP00000369862	ENSP00000344818	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein	ubiquitin C	0.483
COL4A3BP	ZDHHC6	ENSP00000369862	ENSP00000358413	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein	zinc finger, DHHC-type containing 6; Palmitoylates calnexin (CALX), which is required for its association with the ribosome-translocon complex and efficient folding of glycosylated proteins	0.401
DHRS3	AP1S3	ENSP00000365397	ENSP00000379891	dehydrogenase/reductase (SDR family) member 3; Catalyzes the reduction of all-trans-retinal to all- trans-retinol in the presence of NADPH	adaptor-related protein complex 1, sigma 3 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules	0.414
DHRS3	COL4A3BP	ENSP00000365397	ENSP00000369862	dehydrogenase/reductase (SDR family) member 3; Catalyzes the reduction of all-trans-retinal to all- trans-retinol in the presence of NADPH	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein	0.401
DHRS3	UBC	ENSP00000365397	ENSP00000344818	dehydrogenase/reductase (SDR family) member 3; Catalyzes the reduction of all-trans-retinal to all- trans-retinol in the presence of NADPH	ubiquitin C	0.739
DHRS3	ZDHHC6	ENSP00000365397	ENSP00000358413	dehydrogenase/reductase (SDR family) member 3; Catalyzes the reduction of all-trans-retinal to all- trans-retinol in the presence of NADPH	zinc finger, DHHC-type containing 6; Palmitoylates calnexin (CALX), which is required for its association with the ribosome-translocon complex and efficient folding of glycosylated proteins	0.416
GNB4	AP1S3	ENSP00000232564	ENSP00000379891	guanine nucleotide binding protein (G protein), beta polypeptide 4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	adaptor-related protein complex 1, sigma 3 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules	0.460
GNB4	LRRC33	ENSP00000232564	ENSP00000328625	guanine nucleotide binding protein (G protein), beta polypeptide 4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	leucine rich repeat containing 33	0.588
GNB4	UBC	ENSP00000232564	ENSP00000344818	guanine nucleotide binding protein (G protein), beta polypeptide 4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	ubiquitin C	0.956
GNB4	ZDHHC6	ENSP00000232564	ENSP00000358413	guanine nucleotide binding protein (G protein), beta polypeptide 4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	zinc finger, DHHC-type containing 6; Palmitoylates calnexin (CALX), which is required for its association with the ribosome-translocon complex and efficient folding of glycosylated proteins	0.604
LRRC33	AP1S3	ENSP00000328625	ENSP00000379891	leucine rich repeat containing 33	adaptor-related protein complex 1, sigma 3 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules	0.580
LRRC33	GNB4	ENSP00000328625	ENSP00000232564	leucine rich repeat containing 33	guanine nucleotide binding protein (G protein), beta polypeptide 4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	0.588
LRRC33	UBC	ENSP00000328625	ENSP00000344818	leucine rich repeat containing 33	ubiquitin C	0.418

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