Full Link:
  • Version:
  • 10.0 (archived version)
STRINGSTRING
FAM46B FAM46B SMCR7L SMCR7L TAMM41 TAMM41 MB21D2 MB21D2 ITPRIPL2 ITPRIPL2 MAB21L3 MAB21L3 ITPRIP ITPRIP AGGF1 AGGF1
"MAB21L3" - mab-21-like 3 (C. elegans) in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAB21L3mab-21-like 3 (C. elegans) (362 aa)    
Predicted Functional Partners:
MB21D2
Mab-21 domain containing 2 (491 aa)
            score_image   0.614
ITPRIPL2
inositol 1,4,5-trisphosphate receptor interacting protein-like 2 (535 aa)
            score_image   0.590
AGGF1
angiogenic factor with G patch and FHA domains 1; Promotes angiogenesis and the proliferation of endothelial cells. Able to bind to endothelial cells and promote cell proliferation, suggesting that it may act in an autocrine fashion (714 aa)
        score_image       0.571
ITPRIP
inositol 1,4,5-trisphosphate receptor interacting protein; Enhances Ca(2+)-mediated inhibition of inositol 1,4,5- triphosphate receptor (ITPR) Ca(2+) release (547 aa)
            score_image   0.502
TAMM41
TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae); May be involved in the translocation of transit peptide- containing proteins across the mitochondrial inner membrane (By similarity) (316 aa)
            score_image   0.452
SMCR7L
Smith-Magenis syndrome chromosome region, candidate 7-like; Mitochondrial outer membrane protein which regulates mitochondrial morphology. Mitochondrial morphology is controlled by two opposites processes- fusion and fission. Seems to have a key role in inhibiting DNM1L-induced mitochondrial fission (463 aa)
            score_image   0.438
FAM46B
family with sequence similarity 46, member B (425 aa)
            score_image   0.414
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Server load: medium (51%)