RARS2 protein (Homo sapiens) - STRING network view

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Size

small nodes:
protein of unknown 3D structure

large nodes:
some 3D structure is known or predicted

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

RARS2

arginyl-tRNA synthetase 2, mitochondrial (578 aa)

Predicted Functional Partners:

MARS

0.939

YARS

0.918

FARS2

0.915

IARS

0.915

MARS2

0.914

EPRS

0.913

IARS2

0.912

QARS

0.903

WARS2

0.888

LARS2

0.887

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EPRS	FARS2	ENSP00000355890	ENSP00000274680	glutamyl-prolyl-tRNA synthetase	phenylalanyl-tRNA synthetase 2, mitochondrial; Catalyzes direct attachment of p-Tyr (Tyr) to tRNAPhe. Permits also, with a lower efficiency, the attachment of m-Tyr to tRNAPhe, thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins	0.891
EPRS	IARS	ENSP00000355890	ENSP00000364794	glutamyl-prolyl-tRNA synthetase	isoleucyl-tRNA synthetase	0.999
EPRS	IARS2	ENSP00000355890	ENSP00000303279	glutamyl-prolyl-tRNA synthetase	isoleucyl-tRNA synthetase 2, mitochondrial	0.895
EPRS	LARS2	ENSP00000355890	ENSP00000265537	glutamyl-prolyl-tRNA synthetase	leucyl-tRNA synthetase 2, mitochondrial	0.907
EPRS	MARS	ENSP00000355890	ENSP00000262027	glutamyl-prolyl-tRNA synthetase	methionyl-tRNA synthetase	0.999
EPRS	MARS2	ENSP00000355890	ENSP00000282276	glutamyl-prolyl-tRNA synthetase	methionyl-tRNA synthetase 2, mitochondrial	0.986
EPRS	QARS	ENSP00000355890	ENSP00000307567	glutamyl-prolyl-tRNA synthetase	glutaminyl-tRNA synthetase	0.999
EPRS	RARS2	ENSP00000355890	ENSP00000358549	glutamyl-prolyl-tRNA synthetase	arginyl-tRNA synthetase 2, mitochondrial	0.913
EPRS	WARS2	ENSP00000355890	ENSP00000235521	glutamyl-prolyl-tRNA synthetase	tryptophanyl tRNA synthetase 2, mitochondrial	0.745
EPRS	YARS	ENSP00000355890	ENSP00000362576	glutamyl-prolyl-tRNA synthetase	tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction- tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)	0.998
FARS2	EPRS	ENSP00000274680	ENSP00000355890	phenylalanyl-tRNA synthetase 2, mitochondrial; Catalyzes direct attachment of p-Tyr (Tyr) to tRNAPhe. Permits also, with a lower efficiency, the attachment of m-Tyr to tRNAPhe, thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins	glutamyl-prolyl-tRNA synthetase	0.891
FARS2	IARS	ENSP00000274680	ENSP00000364794	phenylalanyl-tRNA synthetase 2, mitochondrial; Catalyzes direct attachment of p-Tyr (Tyr) to tRNAPhe. Permits also, with a lower efficiency, the attachment of m-Tyr to tRNAPhe, thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins	isoleucyl-tRNA synthetase	0.954
FARS2	IARS2	ENSP00000274680	ENSP00000303279	phenylalanyl-tRNA synthetase 2, mitochondrial; Catalyzes direct attachment of p-Tyr (Tyr) to tRNAPhe. Permits also, with a lower efficiency, the attachment of m-Tyr to tRNAPhe, thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins	isoleucyl-tRNA synthetase 2, mitochondrial	0.970
FARS2	LARS2	ENSP00000274680	ENSP00000265537	phenylalanyl-tRNA synthetase 2, mitochondrial; Catalyzes direct attachment of p-Tyr (Tyr) to tRNAPhe. Permits also, with a lower efficiency, the attachment of m-Tyr to tRNAPhe, thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins	leucyl-tRNA synthetase 2, mitochondrial	0.946
FARS2	MARS	ENSP00000274680	ENSP00000262027	phenylalanyl-tRNA synthetase 2, mitochondrial; Catalyzes direct attachment of p-Tyr (Tyr) to tRNAPhe. Permits also, with a lower efficiency, the attachment of m-Tyr to tRNAPhe, thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins	methionyl-tRNA synthetase	0.947
FARS2	MARS2	ENSP00000274680	ENSP00000282276	phenylalanyl-tRNA synthetase 2, mitochondrial; Catalyzes direct attachment of p-Tyr (Tyr) to tRNAPhe. Permits also, with a lower efficiency, the attachment of m-Tyr to tRNAPhe, thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins	methionyl-tRNA synthetase 2, mitochondrial	0.948
FARS2	QARS	ENSP00000274680	ENSP00000307567	phenylalanyl-tRNA synthetase 2, mitochondrial; Catalyzes direct attachment of p-Tyr (Tyr) to tRNAPhe. Permits also, with a lower efficiency, the attachment of m-Tyr to tRNAPhe, thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins	glutaminyl-tRNA synthetase	0.836
FARS2	RARS2	ENSP00000274680	ENSP00000358549	phenylalanyl-tRNA synthetase 2, mitochondrial; Catalyzes direct attachment of p-Tyr (Tyr) to tRNAPhe. Permits also, with a lower efficiency, the attachment of m-Tyr to tRNAPhe, thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins	arginyl-tRNA synthetase 2, mitochondrial	0.915
FARS2	WARS2	ENSP00000274680	ENSP00000235521	phenylalanyl-tRNA synthetase 2, mitochondrial; Catalyzes direct attachment of p-Tyr (Tyr) to tRNAPhe. Permits also, with a lower efficiency, the attachment of m-Tyr to tRNAPhe, thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins	tryptophanyl tRNA synthetase 2, mitochondrial	0.961
FARS2	YARS	ENSP00000274680	ENSP00000362576	phenylalanyl-tRNA synthetase 2, mitochondrial; Catalyzes direct attachment of p-Tyr (Tyr) to tRNAPhe. Permits also, with a lower efficiency, the attachment of m-Tyr to tRNAPhe, thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins	tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction- tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)	0.995

page 1 of 6

Experiments

Neighborhood

Databases

Fusion

Textmining

Cooccurrence

Coexpression

© STRING Consortium 2017

Credits

Access

Info

About