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STRINGSTRING
SYT9 SYT9 TFG TFG RIPPLY2 RIPPLY2 MESP2 MESP2 HES4 HES4
"RIPPLY2" - ripply2 homolog in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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white nodes:
second shell of interactors
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
RIPPLY2ripply2 homolog (zebrafish); Plays a role in somitogenesis. Required for somite segregation and establishment of rostrocaudal polarity in somites (By similarity) (128 aa)    
Predicted Functional Partners:
SYT9
synaptotagmin IX; May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (491 aa)
            score_image   0.472
MESP2
mesoderm posterior 2 homolog (mouse); Transcription factor with important role in somitogenesis. Defines the rostrocaudal patterning of the somite by participating in distinct Notch pathways. Regulates also the FGF signaling pathway. Specifies the rostral half of the somites. Generates rostro-caudal polarity of somites by down-regulating in the presumptive rostral domain DLL1, a Notch ligand. Participates in the segment border formation by activating in the anterior presomitic mesoderm LFNG, a negative regulator of DLL1-Notch signaling. Acts as a strong suppressor of Notch activity. To [...] (397 aa)
            score_image   0.435
HES4
hairy and enhancer of split 4 (Drosophila) (247 aa)
            score_image   0.416
TFG
TRK-fused gene (400 aa)
        score_image       0.400
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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