node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KCNA10 | KCNAB1 | ENSP00000358786 | ENSP00000419952 | potassium voltage-gated channel, shaker-related subfamily, member 10; Mediates voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. The channel activity is up-regulated by cAMP | potassium voltage-gated channel, shaker-related subfamily, beta member 1 | 0.950 |
KCNA10 | KCNAB2 | ENSP00000358786 | ENSP00000367323 | potassium voltage-gated channel, shaker-related subfamily, member 10; Mediates voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. The channel activity is up-regulated by cAMP | potassium voltage-gated channel, shaker-related subfamily, beta member 2 | 0.943 |
KCNA10 | KCNAB3 | ENSP00000358786 | ENSP00000302719 | potassium voltage-gated channel, shaker-related subfamily, member 10; Mediates voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. The channel activity is up-regulated by cAMP | potassium voltage-gated channel, shaker-related subfamily, beta member 3; Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. Alters the functional properties of Kv1.5 | 0.958 |
KCNA10 | KCNH1 | ENSP00000358786 | ENSP00000271751 | potassium voltage-gated channel, shaker-related subfamily, member 10; Mediates voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. The channel activity is up-regulated by cAMP | potassium voltage-gated channel, subfamily H (eag-related), member 1; Pore-forming (alpha) subunit of voltage-gated non- inactivating delayed rectifier potassium channel. Channel properties may be modulated by cAMP and subunit assembly. Mediates IK(NI) current in myoblasts | 0.946 |
KCNA10 | KCNH2 | ENSP00000358786 | ENSP00000262186 | potassium voltage-gated channel, shaker-related subfamily, member 10; Mediates voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. The channel activity is up-regulated by cAMP | potassium voltage-gated channel, subfamily H (eag-related), member 2; Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoform 3 has no channel activity by itself, but modulates channel characteristics when associated with isoform 1 | 0.960 |
KCNA10 | KCNH4 | ENSP00000358786 | ENSP00000264661 | potassium voltage-gated channel, shaker-related subfamily, member 10; Mediates voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. The channel activity is up-regulated by cAMP | potassium voltage-gated channel, subfamily H (eag-related), member 4; Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits an outward current, but shows no inactivation. Channel properties may be modulated by cAMP and subunit assembly | 0.938 |
KCNA10 | KCNH5 | ENSP00000358786 | ENSP00000321427 | potassium voltage-gated channel, shaker-related subfamily, member 10; Mediates voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. The channel activity is up-regulated by cAMP | potassium voltage-gated channel, subfamily H (eag-related), member 5; Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a non-inactivating outward rectifying current. Channel properties may be modulated by cAMP and subunit assembly | 0.955 |
KCNA10 | KCNH6 | ENSP00000358786 | ENSP00000463533 | potassium voltage-gated channel, shaker-related subfamily, member 10; Mediates voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. The channel activity is up-regulated by cAMP | potassium voltage-gated channel, subfamily H (eag-related), member 6; Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a slowly activating, rectifying current (By similarity). Channel properties may be modulated by cAMP and subunit assembly | 0.948 |
KCNA10 | KCNH7 | ENSP00000358786 | ENSP00000331727 | potassium voltage-gated channel, shaker-related subfamily, member 10; Mediates voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. The channel activity is up-regulated by cAMP | potassium voltage-gated channel, subfamily H (eag-related), member 7; Pore-forming (alpha) subunit of voltage-gated potassium channel. Channel properties may be modulated by cAMP and subunit assembly | 0.945 |
KCNA10 | KCNH8 | ENSP00000358786 | ENSP00000328813 | potassium voltage-gated channel, shaker-related subfamily, member 10; Mediates voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. The channel activity is up-regulated by cAMP | potassium voltage-gated channel, subfamily H (eag-related), member 8; Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a slowly activating, outward rectifying current. Channel properties may be modulated by cAMP and subunit assembly | 0.927 |
KCNAB1 | KCNA10 | ENSP00000419952 | ENSP00000358786 | potassium voltage-gated channel, shaker-related subfamily, beta member 1 | potassium voltage-gated channel, shaker-related subfamily, member 10; Mediates voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. The channel activity is up-regulated by cAMP | 0.950 |
KCNAB1 | KCNAB2 | ENSP00000419952 | ENSP00000367323 | potassium voltage-gated channel, shaker-related subfamily, beta member 1 | potassium voltage-gated channel, shaker-related subfamily, beta member 2 | 0.902 |
KCNAB1 | KCNAB3 | ENSP00000419952 | ENSP00000302719 | potassium voltage-gated channel, shaker-related subfamily, beta member 1 | potassium voltage-gated channel, shaker-related subfamily, beta member 3; Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. Alters the functional properties of Kv1.5 | 0.903 |
KCNAB1 | KCNH1 | ENSP00000419952 | ENSP00000271751 | potassium voltage-gated channel, shaker-related subfamily, beta member 1 | potassium voltage-gated channel, subfamily H (eag-related), member 1; Pore-forming (alpha) subunit of voltage-gated non- inactivating delayed rectifier potassium channel. Channel properties may be modulated by cAMP and subunit assembly. Mediates IK(NI) current in myoblasts | 0.924 |
KCNAB1 | KCNH2 | ENSP00000419952 | ENSP00000262186 | potassium voltage-gated channel, shaker-related subfamily, beta member 1 | potassium voltage-gated channel, subfamily H (eag-related), member 2; Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoform 3 has no channel activity by itself, but modulates channel characteristics when associated with isoform 1 | 0.942 |
KCNAB1 | KCNH4 | ENSP00000419952 | ENSP00000264661 | potassium voltage-gated channel, shaker-related subfamily, beta member 1 | potassium voltage-gated channel, subfamily H (eag-related), member 4; Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits an outward current, but shows no inactivation. Channel properties may be modulated by cAMP and subunit assembly | 0.919 |
KCNAB1 | KCNH5 | ENSP00000419952 | ENSP00000321427 | potassium voltage-gated channel, shaker-related subfamily, beta member 1 | potassium voltage-gated channel, subfamily H (eag-related), member 5; Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a non-inactivating outward rectifying current. Channel properties may be modulated by cAMP and subunit assembly | 0.920 |
KCNAB1 | KCNH6 | ENSP00000419952 | ENSP00000463533 | potassium voltage-gated channel, shaker-related subfamily, beta member 1 | potassium voltage-gated channel, subfamily H (eag-related), member 6; Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a slowly activating, rectifying current (By similarity). Channel properties may be modulated by cAMP and subunit assembly | 0.932 |
KCNAB1 | KCNH7 | ENSP00000419952 | ENSP00000331727 | potassium voltage-gated channel, shaker-related subfamily, beta member 1 | potassium voltage-gated channel, subfamily H (eag-related), member 7; Pore-forming (alpha) subunit of voltage-gated potassium channel. Channel properties may be modulated by cAMP and subunit assembly | 0.924 |
KCNAB1 | KCNH8 | ENSP00000419952 | ENSP00000328813 | potassium voltage-gated channel, shaker-related subfamily, beta member 1 | potassium voltage-gated channel, subfamily H (eag-related), member 8; Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a slowly activating, outward rectifying current. Channel properties may be modulated by cAMP and subunit assembly | 0.927 |