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STRINGSTRING
CS CS SLC2A4 SLC2A4 CBLL1 CBLL1 LDHA LDHA HIF1A HIF1A SLC2A14 SLC2A14 SLC16A4 SLC16A4 SLC2A1 SLC2A1 BSG BSG CA9 CA9 SLC9A1 SLC9A1
"SLC16A4" - solute carrier family 16, member 4 (monocarboxylic acid transporter 5) in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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white nodes:
second shell of interactors
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
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textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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Score
SLC16A4solute carrier family 16, member 4 (monocarboxylic acid transporter 5) (487 aa)    
Predicted Functional Partners:
BSG
basigin (Ok blood group); Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). May target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes (By similarity) (385 aa)
        score_image   score_image   0.972
CBLL1
Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1; Promotes ubiquitination of several tyrosine- phosphorylated Src substrates, including CDH1, CTTN and DOK1. Targets CDH1 for endocytosis and degradation (By similarity) (491 aa)
            score_image   0.847
LDHA
lactate dehydrogenase A (361 aa)
            score_image   0.567
SLC2A1
solute carrier family 2 (facilitated glucose transporter), member 1; Facilitative glucose transporter. This isoform may be responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses (492 aa)
            score_image   0.536
CA9
carbonic anhydrase IX; Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia (459 aa)
            score_image   0.508
SLC9A1
solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1; Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction (815 aa)
            score_image   0.505
HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. Plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Binds to [...] (826 aa)
            score_image   0.504
SLC2A4
solute carrier family 2 (facilitated glucose transporter), member 4; Insulin-regulated facilitative glucose transporter (509 aa)
            score_image   0.501
CS
citrate synthase (466 aa)
            score_image   0.499
SLC2A14
solute carrier family 2 (facilitated glucose transporter), member 14; Facilitative glucose transporter (By similarity). May have a specific function related to spermatogenesis (520 aa)
            score_image   0.479
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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