| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMIGO1 | AMIGO2 | ENSP00000358878 | ENSP00000266581 | adhesion molecule with Ig-like domain 1; Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain (By similarity) | adhesion molecule with Ig-like domain 2; Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas | 0.584 |
| AMIGO1 | AMIGO3 | ENSP00000358878 | ENSP00000323096 | adhesion molecule with Ig-like domain 1; Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain (By similarity) | adhesion molecule with Ig-like domain 3; May mediate heterophilic cell-cell interaction. May contribute to signal transduction through its intracellular domain (By similarity) | 0.608 |
| AMIGO1 | CSN1S1 | ENSP00000358878 | ENSP00000246891 | adhesion molecule with Ig-like domain 1; Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain (By similarity) | casein alpha s1; Important role in the capacity of milk to transport calcium phosphate | 0.585 |
| AMIGO1 | DLG1 | ENSP00000358878 | ENSP00000345731 | adhesion molecule with Ig-like domain 1; Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain (By similarity) | discs, large homolog 1 (Drosophila) | 0.681 |
| AMIGO1 | FEZF1 | ENSP00000358878 | ENSP00000411145 | adhesion molecule with Ig-like domain 1; Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain (By similarity) | FEZ family zinc finger 1; Transcription repressor. Involved in the axonal projection and proper termination of olfactory sensory neurons (OSN). Plays a role in rostro-caudal patterning of the diencephalon and in prethalamic formation. Expression is required in OSN to cell-autonomously regulate OSN axon projections. Regulates non-cell-autonomously the layer formation of the olfactory bulb development and the interneurons. May be required for correct rostral migration of the interneuron progenitors (By similarity) | 0.472 |
| AMIGO1 | GMPPB | ENSP00000358878 | ENSP00000309092 | adhesion molecule with Ig-like domain 1; Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain (By similarity) | GDP-mannose pyrophosphorylase B | 0.567 |
| AMIGO1 | HMGB1 | ENSP00000358878 | ENSP00000343040 | adhesion molecule with Ig-like domain 1; Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain (By similarity) | high mobility group box 1; DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells (By similarity) | 0.825 |
| AMIGO1 | NUMA1 | ENSP00000358878 | ENSP00000377298 | adhesion molecule with Ig-like domain 1; Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain (By similarity) | nuclear mitotic apparatus protein 1; Highly abundant component of the nuclear matrix where it may serve a non-mitotic structural role, occupies the majority if the nuclear volume. Required for maintenance and establishment of the mitotic spindle poles, functionning as a tether linking bulk microtubules of the spindle to centrosomes. May be involved in coordination of the alignment of the mitotic spindle to the cellular polarity axis, which is a prerequisite for asymmetric cell divisions | 0.470 |
| AMIGO1 | PHB2 | ENSP00000358878 | ENSP00000441875 | adhesion molecule with Ig-like domain 1; Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain (By similarity) | prohibitin 2; Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging | 0.450 |
| AMIGO1 | RCBTB1 | ENSP00000358878 | ENSP00000258646 | adhesion molecule with Ig-like domain 1; Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain (By similarity) | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1; May be involved in cell cycle regulation by chromatin remodeling | 0.751 |
| AMIGO2 | AMIGO1 | ENSP00000266581 | ENSP00000358878 | adhesion molecule with Ig-like domain 2; Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas | adhesion molecule with Ig-like domain 1; Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain (By similarity) | 0.584 |
| AMIGO2 | AMIGO3 | ENSP00000266581 | ENSP00000323096 | adhesion molecule with Ig-like domain 2; Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas | adhesion molecule with Ig-like domain 3; May mediate heterophilic cell-cell interaction. May contribute to signal transduction through its intracellular domain (By similarity) | 0.630 |
| AMIGO2 | GMPPB | ENSP00000266581 | ENSP00000309092 | adhesion molecule with Ig-like domain 2; Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas | GDP-mannose pyrophosphorylase B | 0.572 |
| AMIGO3 | AMIGO1 | ENSP00000323096 | ENSP00000358878 | adhesion molecule with Ig-like domain 3; May mediate heterophilic cell-cell interaction. May contribute to signal transduction through its intracellular domain (By similarity) | adhesion molecule with Ig-like domain 1; Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain (By similarity) | 0.608 |
| AMIGO3 | AMIGO2 | ENSP00000323096 | ENSP00000266581 | adhesion molecule with Ig-like domain 3; May mediate heterophilic cell-cell interaction. May contribute to signal transduction through its intracellular domain (By similarity) | adhesion molecule with Ig-like domain 2; Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas | 0.630 |
| AMIGO3 | GMPPB | ENSP00000323096 | ENSP00000309092 | adhesion molecule with Ig-like domain 3; May mediate heterophilic cell-cell interaction. May contribute to signal transduction through its intracellular domain (By similarity) | GDP-mannose pyrophosphorylase B | 0.710 |
| CSN1S1 | AMIGO1 | ENSP00000246891 | ENSP00000358878 | casein alpha s1; Important role in the capacity of milk to transport calcium phosphate | adhesion molecule with Ig-like domain 1; Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain (By similarity) | 0.585 |
| CSN1S1 | FEZF1 | ENSP00000246891 | ENSP00000411145 | casein alpha s1; Important role in the capacity of milk to transport calcium phosphate | FEZ family zinc finger 1; Transcription repressor. Involved in the axonal projection and proper termination of olfactory sensory neurons (OSN). Plays a role in rostro-caudal patterning of the diencephalon and in prethalamic formation. Expression is required in OSN to cell-autonomously regulate OSN axon projections. Regulates non-cell-autonomously the layer formation of the olfactory bulb development and the interneurons. May be required for correct rostral migration of the interneuron progenitors (By similarity) | 0.700 |
| CSN1S1 | NUMA1 | ENSP00000246891 | ENSP00000377298 | casein alpha s1; Important role in the capacity of milk to transport calcium phosphate | nuclear mitotic apparatus protein 1; Highly abundant component of the nuclear matrix where it may serve a non-mitotic structural role, occupies the majority if the nuclear volume. Required for maintenance and establishment of the mitotic spindle poles, functionning as a tether linking bulk microtubules of the spindle to centrosomes. May be involved in coordination of the alignment of the mitotic spindle to the cellular polarity axis, which is a prerequisite for asymmetric cell divisions | 0.659 |
| CSN1S1 | PHB2 | ENSP00000246891 | ENSP00000441875 | casein alpha s1; Important role in the capacity of milk to transport calcium phosphate | prohibitin 2; Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging | 0.721 |
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