Full Link:
  • Version:
  • 10.0 (archived version)
STRINGSTRING
GABPA GABPA UBC UBC COX7A2 COX7A2 MT-CO2 MT-CO2 COX7C COX7C NDUFC2 NDUFC2 COX6A1 COX6A1 ENSG00000259112 ENSG00000259112 COX6B1 COX6B1 COX5A COX5A COX6A2 COX6A2
"COX7A2" - cytochrome c oxidase subunit VIIa polypeptide 2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
COX7A2cytochrome c oxidase subunit VIIa polypeptide 2 (liver); This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport (115 aa)    
Predicted Functional Partners:
MT-CO2
mitochondrially encoded cytochrome c oxidase II; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1 (By similarity) (227 aa)
        score_image       0.999
UBC
ubiquitin C (685 aa)
        score_image       0.730
COX7C
cytochrome c oxidase subunit VIIc; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport (63 aa)
      score_image     score_image   0.616
COX6A1
cytochrome c oxidase subunit VIa polypeptide 1; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport (109 aa)
      score_image     score_image   0.605
COX6A2
cytochrome c oxidase subunit VIa polypeptide 2; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport (97 aa)
      score_image     score_image   0.543
ENSG00000259112
NDUFC2-KCTD14 readthrough; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity) (114 aa)
      score_image     score_image   0.542
COX6B1
cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous); Connects the two COX monomers into the physiological dimeric form (By similarity) (86 aa)
      score_image     score_image   0.535
NDUFC2
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity) (119 aa)
      score_image     score_image   0.527
COX5A
cytochrome c oxidase subunit Va; This is the heme A-containing chain of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport (150 aa)
      score_image     score_image   0.485
GABPA
GA binding protein transcription factor, alpha subunit 60kDa; Transcription factor capable of interacting with purine rich repeats (GA repeats). Necessary for the expression of the Adenovirus E4 gene (454 aa)
            score_image   0.472
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Server load: medium (47%)