node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGL | AMY1A | ENSP00000294724 | ENSP00000359100 | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | amylase, alpha 1A (salivary) | 0.910 |
AGL | GBE1 | ENSP00000294724 | ENSP00000410833 | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | glucan (1,4-alpha-), branching enzyme 1; Required for sufficient glycogen accumulation. The alpha 1-6 branches of glycogen play an important role in increasing the solubility of the molecule and, consequently, in reducing the osmotic pressure within cells | 0.996 |
AGL | PYGB | ENSP00000294724 | ENSP00000216962 | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | phosphorylase, glycogen; brain; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) | 0.998 |
AGL | PYGL | ENSP00000294724 | ENSP00000216392 | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | phosphorylase, glycogen, liver; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) | 0.998 |
AGL | SI | ENSP00000294724 | ENSP00000264382 | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | sucrase-isomaltase (alpha-glucosidase); Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides | 0.905 |
AKAP1 | AKAP8 | ENSP00000337736 | ENSP00000269701 | A kinase (PRKA) anchor protein 1; Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane | A kinase (PRKA) anchor protein 8; Anchoring protein that mediates the subcellular compartmentation of cAMP-dependent protein kinase (PKA type II) | 0.754 |
AKAP1 | AMY1A | ENSP00000337736 | ENSP00000359100 | A kinase (PRKA) anchor protein 1; Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane | amylase, alpha 1A (salivary) | 0.576 |
AKAP8 | AKAP1 | ENSP00000269701 | ENSP00000337736 | A kinase (PRKA) anchor protein 8; Anchoring protein that mediates the subcellular compartmentation of cAMP-dependent protein kinase (PKA type II) | A kinase (PRKA) anchor protein 1; Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane | 0.754 |
AKAP8 | AMY1A | ENSP00000269701 | ENSP00000359100 | A kinase (PRKA) anchor protein 8; Anchoring protein that mediates the subcellular compartmentation of cAMP-dependent protein kinase (PKA type II) | amylase, alpha 1A (salivary) | 0.576 |
AMY1A | AGL | ENSP00000359100 | ENSP00000294724 | amylase, alpha 1A (salivary) | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 0.910 |
AMY1A | AKAP1 | ENSP00000359100 | ENSP00000337736 | amylase, alpha 1A (salivary) | A kinase (PRKA) anchor protein 1; Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane | 0.576 |
AMY1A | AKAP8 | ENSP00000359100 | ENSP00000269701 | amylase, alpha 1A (salivary) | A kinase (PRKA) anchor protein 8; Anchoring protein that mediates the subcellular compartmentation of cAMP-dependent protein kinase (PKA type II) | 0.576 |
AMY1A | BPI | ENSP00000359100 | ENSP00000262865 | amylase, alpha 1A (salivary) | bactericidal/permeability-increasing protein | 0.608 |
AMY1A | COL10A1 | ENSP00000359100 | ENSP00000243222 | amylase, alpha 1A (salivary) | collagen, type X, alpha 1; Type X collagen is a product of hypertrophic chondrocytes and has been localized to presumptive mineralization zones of hyaline cartilage | 0.606 |
AMY1A | GBE1 | ENSP00000359100 | ENSP00000410833 | amylase, alpha 1A (salivary) | glucan (1,4-alpha-), branching enzyme 1; Required for sufficient glycogen accumulation. The alpha 1-6 branches of glycogen play an important role in increasing the solubility of the molecule and, consequently, in reducing the osmotic pressure within cells | 0.960 |
AMY1A | LCT | ENSP00000359100 | ENSP00000264162 | amylase, alpha 1A (salivary) | lactase; LPH splits lactose in the small intestine | 0.717 |
AMY1A | PYGB | ENSP00000359100 | ENSP00000216962 | amylase, alpha 1A (salivary) | phosphorylase, glycogen; brain; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) | 0.953 |
AMY1A | PYGL | ENSP00000359100 | ENSP00000216392 | amylase, alpha 1A (salivary) | phosphorylase, glycogen, liver; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) | 0.954 |
AMY1A | SI | ENSP00000359100 | ENSP00000264382 | amylase, alpha 1A (salivary) | sucrase-isomaltase (alpha-glucosidase); Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides | 0.924 |
BPI | AMY1A | ENSP00000262865 | ENSP00000359100 | bactericidal/permeability-increasing protein | amylase, alpha 1A (salivary) | 0.608 |