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STRINGSTRING
ENSG00000259024 ENSG00000259024 C15orf40 C15orf40 UBC UBC TMX4 TMX4 SLC35A3 SLC35A3 TMEM57 TMEM57 SLC35A2 SLC35A2 SLC35D2 SLC35D2 SLC35D1 SLC35D1 LPHN1 LPHN1 SLC35C1 SLC35C1
"SLC35A3" - solute carrier family 35 (UDP-N-acetylglucosamine in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
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query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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Score
SLC35A3solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3; Uridine diphosphate-N-acetylglucosamine transporter in the Golgi apparatus (325 aa)    
Predicted Functional Partners:
SLC35D1
solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1; Transports both UDP-glucuronic acid (UDP-GlcA) and UDP- N-acetylgalactosamine (UDP-GalNAc) from the cytoplasm to into the endoplasmic reticulum lumen. May participate in glucuronidation and/or chondroitin sulfate biosynthesis (355 aa)
             score_image   0.942
LPHN1
latrophilin 1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor propably implicated in the regulation of exocytosis (By similarity) (1474 aa)
             score_image   0.756
SLC35D2
solute carrier family 35, member D2; Antiporter transporting nucleotide sugars such as UDP-N- acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP- mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars). May take part in heparan sulfate synthesis by supplying UDP-Glc-NAc, the donor substrate, and thus be involved in growth factor signaling (337 aa)
             score_image   0.717
SLC35C1
solute carrier family 35, member C1; Involved in GDP-fucose import from the cytoplasm into the Golgi lumen (364 aa)
       score_image     score_image   0.644
TMEM57
transmembrane protein 57 (664 aa)
             score_image   0.617
SLC35A2
solute carrier family 35 (UDP-galactose transporter), member A2; Transports nucleotide sugars from the cytosol into Golgi vesicles where glycosyltransferases function (396 aa)
         score_image   score_image score_image 0.593
TMX4
thioredoxin-related transmembrane protein 4 (349 aa)
             score_image   0.553
ENSG00000259024
FAM18B2-CDRT4 readthrough (164 aa)
             score_image   0.525
UBC
ubiquitin C (685 aa)
         score_image       0.506
C15orf40
chromosome 15 open reading frame 40 (167 aa)
             score_image   0.499
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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