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STRINGSTRING
CSNK1G3 CSNK1G3 FAM71E2 FAM71E2 TEX19 TEX19 HLCS HLCS TMEM56 TMEM56 AP3S1 AP3S1 FOCAD FOCAD COMMD7 COMMD7 GBAS GBAS SFMBT1 SFMBT1
"TMEM56" - transmembrane protein 56 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
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Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM56transmembrane protein 56 (263 aa)    
Predicted Functional Partners:
COMMD7
COMM domain containing 7; Associates with the NF-kappa-B complex and suppresses its transcriptional activity (200 aa)
            score_image   0.691
FOCAD
focadhesin; Potential tumor suppressor in gliomas (By similarity) (1801 aa)
            score_image   0.570
CSNK1G3
casein kinase 1, gamma 3; Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate (By similarity) (455 aa)
            score_image   0.487
HLCS
holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase); Post-translational modification of specific protein by attachment of biotin. Acts on various carboxylases such as acetyl- CoA-carboxylase, pyruvate carboxylase, propionyl CoA carboxylase, and 3-methylcrotonyl CoA carboxylase (726 aa)
            score_image   0.486
SFMBT1
Scm-like with four mbt domains 1 (866 aa)
            score_image   0.470
GBAS
glioblastoma amplified sequence (286 aa)
            score_image   0.469
AP3S1
adaptor-related protein complex 3, sigma 1 subunit; Part of the AP-3 complex, an adapter-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals (193 aa)
            score_image   0.453
FAM71E2
family with sequence similarity 71, member E2 (922 aa)
            score_image   0.418
TEX19
testis expressed 19 (164 aa)
            score_image   0.418
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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