| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EXOSC10 | UBC | ENSP00000366135 | ENSP00000344818 | exosome component 10; Putative catalytic component of the RNA exosome complex which has 3’->5’ exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding ’pervasive’ transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. [...] | ubiquitin C | 0.813 |
| EXOSC10 | YTHDF1 | ENSP00000366135 | ENSP00000359364 | exosome component 10; Putative catalytic component of the RNA exosome complex which has 3’->5’ exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding ’pervasive’ transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. [...] | YTH domain family, member 1 | 0.663 |
| EXOSC10 | ZFC3H1 | ENSP00000366135 | ENSP00000368017 | exosome component 10; Putative catalytic component of the RNA exosome complex which has 3’->5’ exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding ’pervasive’ transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. [...] | zinc finger, C3H1-type containing | 0.726 |
| G3BP1 | UBC | ENSP00000348578 | ENSP00000344818 | GTPase activating protein (SH3 domain) binding protein 1; May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3’-UTR. ATP- and magnesium- dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3’ tail or hanging tails at both 5’- and 3’-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in [...] | ubiquitin C | 0.983 |
| G3BP1 | YTHDF1 | ENSP00000348578 | ENSP00000359364 | GTPase activating protein (SH3 domain) binding protein 1; May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3’-UTR. ATP- and magnesium- dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3’ tail or hanging tails at both 5’- and 3’-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in [...] | YTH domain family, member 1 | 0.758 |
| LRSAM1 | UBC | ENSP00000300417 | ENSP00000344818 | leucine rich repeat and sterile alpha motif containing 1; E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivate the ability of TSG101 to sort endocytic (EGF receptors) and exocytic (HIV-1 viral proteins) cargos | ubiquitin C | 0.945 |
| LRSAM1 | YTHDF1 | ENSP00000300417 | ENSP00000359364 | leucine rich repeat and sterile alpha motif containing 1; E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivate the ability of TSG101 to sort endocytic (EGF receptors) and exocytic (HIV-1 viral proteins) cargos | YTH domain family, member 1 | 0.644 |
| NQO1 | UBC | ENSP00000319788 | ENSP00000344818 | NAD(P)H dehydrogenase, quinone 1; The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis | ubiquitin C | 0.837 |
| NQO1 | YTHDF1 | ENSP00000319788 | ENSP00000359364 | NAD(P)H dehydrogenase, quinone 1; The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis | YTH domain family, member 1 | 0.644 |
| PCDHB14 | YTHDF1 | ENSP00000239449 | ENSP00000359364 | protocadherin beta 14; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain (By similarity) | YTH domain family, member 1 | 0.510 |
| SERPINH1 | UBC | ENSP00000350894 | ENSP00000344818 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1); Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen | ubiquitin C | 0.965 |
| SERPINH1 | YTHDF1 | ENSP00000350894 | ENSP00000359364 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1); Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen | YTH domain family, member 1 | 0.644 |
| UBC | EXOSC10 | ENSP00000344818 | ENSP00000366135 | ubiquitin C | exosome component 10; Putative catalytic component of the RNA exosome complex which has 3’->5’ exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding ’pervasive’ transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. [...] | 0.813 |
| UBC | G3BP1 | ENSP00000344818 | ENSP00000348578 | ubiquitin C | GTPase activating protein (SH3 domain) binding protein 1; May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3’-UTR. ATP- and magnesium- dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3’ tail or hanging tails at both 5’- and 3’-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in [...] | 0.983 |
| UBC | LRSAM1 | ENSP00000344818 | ENSP00000300417 | ubiquitin C | leucine rich repeat and sterile alpha motif containing 1; E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivate the ability of TSG101 to sort endocytic (EGF receptors) and exocytic (HIV-1 viral proteins) cargos | 0.945 |
| UBC | NQO1 | ENSP00000344818 | ENSP00000319788 | ubiquitin C | NAD(P)H dehydrogenase, quinone 1; The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis | 0.837 |
| UBC | SERPINH1 | ENSP00000344818 | ENSP00000350894 | ubiquitin C | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1); Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen | 0.965 |
| UBC | YTHDF1 | ENSP00000344818 | ENSP00000359364 | ubiquitin C | YTH domain family, member 1 | 0.647 |
| UBC | ZFC3H1 | ENSP00000344818 | ENSP00000368017 | ubiquitin C | zinc finger, C3H1-type containing | 0.483 |
| UBC | ZNF687 | ENSP00000344818 | ENSP00000319829 | ubiquitin C | zinc finger protein 687; May be involved in transcriptional regulation | 0.416 |
Share
