Full Link:
  • Version:
  • 10.0 (archived version)
STRINGSTRING
NLRP5 NLRP5 DDX53 DDX53 TLE6 TLE6 GTSF1L GTSF1L DDX43 DDX43 OOEP OOEP PSMA8 PSMA8 KHDC1 KHDC1 KRT14 KRT14 CES2 CES2 CES5A CES5A
"OOEP" - oocyte expressed protein in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OOEPoocyte expressed protein; As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions (By similarity) (149 aa)    
Predicted Functional Partners:
KHDC1
KH homology domain containing 1 (164 aa)
            score_image   0.889
TLE6
transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila); As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions (By similarity) (572 aa)
        score_image   score_image   0.816
GTSF1L
gametocyte specific factor 1-like (148 aa)
            score_image   0.514
KRT14
keratin 14; The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro (472 aa)
            score_image   0.508
DDX53
DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 (631 aa)
            score_image   0.489
DDX43
DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 (648 aa)
            score_image   0.489
CES2
carboxylesterase 2; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows high catalytic efficiency for hydrolysis of cocaine, 4-methylumbelliferyl acetate, heroin and 6-monoacetylmorphine (623 aa)
            score_image   0.485
CES5A
carboxylesterase 5A; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs (By similarity) (604 aa)
            score_image   0.452
NLRP5
NLR family, pyrin domain containing 5; As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions (By similarity) (1200 aa)
        score_image   score_image   0.441
PSMA8
proteasome (prosome, macropain) subunit, alpha type, 8; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity). This may be a testis-specific subunit (256 aa)
            score_image   0.416
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Server load: low (27%)