node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CES2 | CES5A | ENSP00000317842 | ENSP00000428864 | carboxylesterase 2; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows high catalytic efficiency for hydrolysis of cocaine, 4-methylumbelliferyl acetate, heroin and 6-monoacetylmorphine | carboxylesterase 5A; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs (By similarity) | 0.906 |
CES2 | OOEP | ENSP00000317842 | ENSP00000359384 | carboxylesterase 2; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows high catalytic efficiency for hydrolysis of cocaine, 4-methylumbelliferyl acetate, heroin and 6-monoacetylmorphine | oocyte expressed protein; As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions (By similarity) | 0.485 |
CES5A | CES2 | ENSP00000428864 | ENSP00000317842 | carboxylesterase 5A; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs (By similarity) | carboxylesterase 2; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows high catalytic efficiency for hydrolysis of cocaine, 4-methylumbelliferyl acetate, heroin and 6-monoacetylmorphine | 0.906 |
CES5A | OOEP | ENSP00000428864 | ENSP00000359384 | carboxylesterase 5A; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs (By similarity) | oocyte expressed protein; As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions (By similarity) | 0.452 |
DDX43 | OOEP | ENSP00000359361 | ENSP00000359384 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 | oocyte expressed protein; As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions (By similarity) | 0.489 |
DDX53 | OOEP | ENSP00000368667 | ENSP00000359384 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 | oocyte expressed protein; As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions (By similarity) | 0.489 |
GTSF1L | OOEP | ENSP00000362094 | ENSP00000359384 | gametocyte specific factor 1-like | oocyte expressed protein; As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions (By similarity) | 0.514 |
GTSF1L | PSMA8 | ENSP00000362094 | ENSP00000311121 | gametocyte specific factor 1-like | proteasome (prosome, macropain) subunit, alpha type, 8; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity). This may be a testis-specific subunit | 0.639 |
KHDC1 | OOEP | ENSP00000257765 | ENSP00000359384 | KH homology domain containing 1 | oocyte expressed protein; As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions (By similarity) | 0.889 |
KRT14 | OOEP | ENSP00000167586 | ENSP00000359384 | keratin 14; The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro | oocyte expressed protein; As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions (By similarity) | 0.508 |
NLRP5 | OOEP | ENSP00000375063 | ENSP00000359384 | NLR family, pyrin domain containing 5; As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions (By similarity) | oocyte expressed protein; As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions (By similarity) | 0.441 |
OOEP | CES2 | ENSP00000359384 | ENSP00000317842 | oocyte expressed protein; As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions (By similarity) | carboxylesterase 2; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows high catalytic efficiency for hydrolysis of cocaine, 4-methylumbelliferyl acetate, heroin and 6-monoacetylmorphine | 0.485 |
OOEP | CES5A | ENSP00000359384 | ENSP00000428864 | oocyte expressed protein; As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions (By similarity) | carboxylesterase 5A; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs (By similarity) | 0.452 |
OOEP | DDX43 | ENSP00000359384 | ENSP00000359361 | oocyte expressed protein; As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions (By similarity) | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 | 0.489 |
OOEP | DDX53 | ENSP00000359384 | ENSP00000368667 | oocyte expressed protein; As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions (By similarity) | DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 | 0.489 |
OOEP | GTSF1L | ENSP00000359384 | ENSP00000362094 | oocyte expressed protein; As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions (By similarity) | gametocyte specific factor 1-like | 0.514 |
OOEP | KHDC1 | ENSP00000359384 | ENSP00000257765 | oocyte expressed protein; As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions (By similarity) | KH homology domain containing 1 | 0.889 |
OOEP | KRT14 | ENSP00000359384 | ENSP00000167586 | oocyte expressed protein; As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions (By similarity) | keratin 14; The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro | 0.508 |
OOEP | NLRP5 | ENSP00000359384 | ENSP00000375063 | oocyte expressed protein; As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions (By similarity) | NLR family, pyrin domain containing 5; As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions (By similarity) | 0.441 |
OOEP | PSMA8 | ENSP00000359384 | ENSP00000311121 | oocyte expressed protein; As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions (By similarity) | proteasome (prosome, macropain) subunit, alpha type, 8; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity). This may be a testis-specific subunit | 0.416 |