Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
|
Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | TMEM185A | transmembrane protein 185A (350 aa) | ||||||||||||
Predicted Functional Partners:
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 | GPR107 | G protein-coupled receptor 107 (600 aa) |
 |
0.802 | ||||||||||
 | GPR108 | G protein-coupled receptor 108 (543 aa) |
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0.770 | ||||||||||
 | PAQR5 | progestin and adipoQ receptor family member V; Steroid membrane receptor. Binds progesterone. May be involved in oocyte maturation (330 aa) |
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0.743 | ||||||||||
 | GPR149 | G protein-coupled receptor 149; Orphan receptor (731 aa) |
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0.732 | ||||||||||
 | PAQR8 | progestin and adipoQ receptor family member VIII; Steroid membrane receptor. Binds progesterone. May be involved in oocyte maturation (By similarity) (354 aa) |
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0.672 | ||||||||||
 | PAQR7 | progestin and adipoQ receptor family member VII; Steroid membrane receptor. Binds progesterone in vitro. May be involved in oocyte maturation (346 aa) |
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0.647 | ||||||||||
 | GPR137 | G protein-coupled receptor 137 (475 aa) |
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0.630 | ||||||||||
 | C11orf92 | chromosome 11 open reading frame 92 (124 aa) |
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0.627 | ||||||||||
 | MAGEA11 | melanoma antigen family A, 11; Acts as androgen receptor co-regulator that increases androgen receptor activity by modulating the receptors interdomain interaction. May play a role in embryonal development and tumor transformation or aspects of tumor progression (429 aa) |
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0.624 | ||||||||||
 | PAQR6 | progestin and adipoQ receptor family member VI (351 aa) |
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0.590 | ||||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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