Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but resolution at 400 dpi
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as simple tabular text output:
TSV: tab separated values - can be opened in Excel
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and annotated functions of the network proteins
Browse interactions in tabular form:
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CLCA4 | CNGA3 | ENSP00000359594 | ENSP00000272602 | chloride channel accessory 4; May be involved in mediating calcium-activated chloride conductance | cyclic nucleotide gated channel alpha 3; Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of cone photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGB3 (By similarity). Essential for the generation of light-evoked elec [...] | 0.800 |
CLCA4 | CNGA4 | ENSP00000359594 | ENSP00000369268 | chloride channel accessory 4; May be involved in mediating calcium-activated chloride conductance | cyclic nucleotide gated channel alpha 4; Second messenger, cAMP, causes the opening of cation- selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection (By similarity) | 0.800 |
CLCA4 | CWH43 | ENSP00000359594 | ENSP00000226432 | chloride channel accessory 4; May be involved in mediating calcium-activated chloride conductance | cell wall biogenesis 43 C-terminal homolog (S. cerevisiae); Involved in lipid remodeling during GPI-anchor maturation (By similarity) | 0.418 |
CLCA4 | GLIPR2 | ENSP00000359594 | ENSP00000367196 | chloride channel accessory 4; May be involved in mediating calcium-activated chloride conductance | GLI pathogenesis-related 2 | 0.403 |
CLCA4 | ODF2L | ENSP00000359594 | ENSP00000359600 | chloride channel accessory 4; May be involved in mediating calcium-activated chloride conductance | outer dense fiber of sperm tails 2-like | 0.430 |
CLCA4 | POLD1 | ENSP00000359594 | ENSP00000406046 | chloride channel accessory 4; May be involved in mediating calcium-activated chloride conductance | polymerase (DNA directed), delta 1, catalytic subunit; Possesses two enzymatic activities- DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3’- to 5’-direction. Required with its accessory proteins (proliferating cell nuclear antigen (PCNA) and replication factor C (RFC) or activator 1) for leading strand synthesis. Also involved in completing Okazaki fragments initiated by the DNA polymerase alpha/primase complex | 0.656 |
CLCA4 | TCEAL2 | ENSP00000359594 | ENSP00000332359 | chloride channel accessory 4; May be involved in mediating calcium-activated chloride conductance | transcription elongation factor A (SII)-like 2; May be involved in transcriptional regulation | 0.404 |
CNGA3 | CLCA4 | ENSP00000272602 | ENSP00000359594 | cyclic nucleotide gated channel alpha 3; Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of cone photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGB3 (By similarity). Essential for the generation of light-evoked elec [...] | chloride channel accessory 4; May be involved in mediating calcium-activated chloride conductance | 0.800 |
CNGA4 | CLCA4 | ENSP00000369268 | ENSP00000359594 | cyclic nucleotide gated channel alpha 4; Second messenger, cAMP, causes the opening of cation- selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection (By similarity) | chloride channel accessory 4; May be involved in mediating calcium-activated chloride conductance | 0.800 |
CWH43 | CLCA4 | ENSP00000226432 | ENSP00000359594 | cell wall biogenesis 43 C-terminal homolog (S. cerevisiae); Involved in lipid remodeling during GPI-anchor maturation (By similarity) | chloride channel accessory 4; May be involved in mediating calcium-activated chloride conductance | 0.418 |
GLIPR2 | CLCA4 | ENSP00000367196 | ENSP00000359594 | GLI pathogenesis-related 2 | chloride channel accessory 4; May be involved in mediating calcium-activated chloride conductance | 0.403 |
ODF2L | CLCA4 | ENSP00000359600 | ENSP00000359594 | outer dense fiber of sperm tails 2-like | chloride channel accessory 4; May be involved in mediating calcium-activated chloride conductance | 0.430 |
POLD1 | CLCA4 | ENSP00000406046 | ENSP00000359594 | polymerase (DNA directed), delta 1, catalytic subunit; Possesses two enzymatic activities- DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3’- to 5’-direction. Required with its accessory proteins (proliferating cell nuclear antigen (PCNA) and replication factor C (RFC) or activator 1) for leading strand synthesis. Also involved in completing Okazaki fragments initiated by the DNA polymerase alpha/primase complex | chloride channel accessory 4; May be involved in mediating calcium-activated chloride conductance | 0.656 |
TCEAL2 | CLCA4 | ENSP00000332359 | ENSP00000359594 | transcription elongation factor A (SII)-like 2; May be involved in transcriptional regulation | chloride channel accessory 4; May be involved in mediating calcium-activated chloride conductance | 0.404 |