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LPAR4 LPAR4 GPR65 GPR65 LPAR6 LPAR6 GPR4 GPR4 LPAR5 LPAR5 P2RY10 P2RY10 BDKRB1 BDKRB1 LPAR3 LPAR3 CXCL12 CXCL12 EGFR EGFR PLD2 PLD2
"LPAR3" - lysophosphatidic acid receptor 3 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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second shell of interactors
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experiment edge
experimentally determined
Predicted Interactions
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fusion edge
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cooccurrence edge
gene co-occurrence
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textmining
coexpression edge
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protein homology
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LPAR3lysophosphatidic acid receptor 3; Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. May play a role in the development of ovarian cancer. Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins (353 aa)    
Predicted Functional Partners:
EGFR
epidermal growth factor receptor (1210 aa)
          score_image score_image   0.986
CXCL12
chemokine (C-X-C motif) ligand 12 (140 aa)
          score_image score_image   0.981
LPAR4
lysophosphatidic acid receptor 4; Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Transduces a signal by increasing the intracellular calcium ions and by stimulating adenylyl cyclase activity. The rank order of potency for agonists of this receptor is 1-oleoyl- > 1-stearoyl- > 1-palmitoyl- > 1-myristoyl- > 1- alkyl- > 1-alkenyl-LPA (370 aa)
          score_image score_image   0.974
LPAR6
lysophosphatidic acid receptor 6 (344 aa)
          score_image score_image   0.964
LPAR5
lysophosphatidic acid receptor 5; Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities (372 aa)
          score_image score_image   0.961
GPR4
G protein-coupled receptor 4; Proton-sensing receptor coupled to several G-proteins, including G(s), G(13) and G(q)/G(11) proteins, leading to cAMP production (362 aa)
          score_image score_image   0.952
BDKRB1
bradykinin receptor B1; This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation (353 aa)
          score_image score_image   0.949
P2RY10
purinergic receptor P2Y, G-protein coupled, 10; Putative receptor for purines coupled to G-proteins (339 aa)
          score_image score_image   0.948
GPR65
G protein-coupled receptor 65; Receptor for the glycosphingolipid psychosine (PSY) and several related glycosphingolipids. May have a role in activation- induced cell death or differentiation of T-cells (337 aa)
          score_image score_image   0.941
PLD2
phospholipase D2; May have a role in signal-induced cytoskeletal regulation and/or endocytosis (By similarity) (933 aa)
          score_image score_image   0.933
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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