Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
|
Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | KIAA1586 | KIAA1586 (787 aa) | ||||||||||||
Predicted Functional Partners:
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 | UBC | ubiquitin C (685 aa) |
 |
0.802 | ||||||||||
 | DNAJC18 | DnaJ (Hsp40) homolog, subfamily C, member 18 (358 aa) |
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0.519 | ||||||||||
 | OR1C1 | olfactory receptor, family 1, subfamily C, member 1; Odorant receptor (Potential) (314 aa) |
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0.504 | ||||||||||
 | OR4M2 | olfactory receptor, family 4, subfamily M, member 2; Odorant receptor (Potential) (313 aa) |
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0.503 | ||||||||||
 | ODF3L2 | outer dense fiber of sperm tails 3-like 2 (289 aa) |
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0.501 | ||||||||||
 | ZNF280C | zinc finger protein 280C; May function as a transcription factor (737 aa) |
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0.499 | ||||||||||
 | OR4N4 | olfactory receptor, family 4, subfamily N, member 4; Odorant receptor (Potential) (316 aa) |
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0.499 | ||||||||||
 | ZMYM1 | zinc finger, MYM-type 1 (1142 aa) |
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0.471 | ||||||||||
 | RNF148 | ring finger protein 148 (305 aa) |
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0.468 | ||||||||||
 | RNF133 | ring finger protein 133; Has E3 ubiquitin-protein ligase activity (By similarity) (376 aa) |
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0.424 | ||||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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