node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGPS | FAM73A | ENSP00000264167 | ENSP00000359827 | alkylglycerone phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids (By similarity) | family with sequence similarity 73, member A | 0.533 |
AGPS | HPS5 | ENSP00000264167 | ENSP00000265967 | alkylglycerone phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids (By similarity) | Hermansky-Pudlak syndrome 5; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Regulates intracellular vesicular trafficking in fibroblasts. May be involved in the regulation of general functions of integrins | 0.483 |
BLMH | FAM73A | ENSP00000261714 | ENSP00000359827 | bleomycin hydrolase; The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B- aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity (By similarity) | family with sequence similarity 73, member A | 0.591 |
DNAJC14 | FAM73A | ENSP00000316240 | ENSP00000359827 | DnaJ (Hsp40) homolog, subfamily C, member 14; Regulates the export of target proteins, such as DRD1, from the endoplasmic reticulum to the cell surface (By similarity) | family with sequence similarity 73, member A | 0.497 |
DNAJC14 | HPS5 | ENSP00000316240 | ENSP00000265967 | DnaJ (Hsp40) homolog, subfamily C, member 14; Regulates the export of target proteins, such as DRD1, from the endoplasmic reticulum to the cell surface (By similarity) | Hermansky-Pudlak syndrome 5; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Regulates intracellular vesicular trafficking in fibroblasts. May be involved in the regulation of general functions of integrins | 0.449 |
ENSG00000257390 | FAM73A | ENSP00000447000 | ENSP00000359827 | Uncharacterized protein | family with sequence similarity 73, member A | 0.497 |
ENSG00000257390 | HPS5 | ENSP00000447000 | ENSP00000265967 | Uncharacterized protein | Hermansky-Pudlak syndrome 5; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Regulates intracellular vesicular trafficking in fibroblasts. May be involved in the regulation of general functions of integrins | 0.449 |
FAM73A | AGPS | ENSP00000359827 | ENSP00000264167 | family with sequence similarity 73, member A | alkylglycerone phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids (By similarity) | 0.533 |
FAM73A | BLMH | ENSP00000359827 | ENSP00000261714 | family with sequence similarity 73, member A | bleomycin hydrolase; The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B- aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity (By similarity) | 0.591 |
FAM73A | DNAJC14 | ENSP00000359827 | ENSP00000316240 | family with sequence similarity 73, member A | DnaJ (Hsp40) homolog, subfamily C, member 14; Regulates the export of target proteins, such as DRD1, from the endoplasmic reticulum to the cell surface (By similarity) | 0.497 |
FAM73A | ENSG00000257390 | ENSP00000359827 | ENSP00000447000 | family with sequence similarity 73, member A | Uncharacterized protein | 0.497 |
FAM73A | HNRNPA0 | ENSP00000359827 | ENSP00000316042 | family with sequence similarity 73, member A | heterogeneous nuclear ribonucleoprotein A0; mRNA-binding component of ribonucleosomes. Specifically binds AU-rich element (ARE)-containing mRNAs. Involved in post- transcriptional regulation of cytokines mRNAs | 0.505 |
FAM73A | HPS5 | ENSP00000359827 | ENSP00000265967 | family with sequence similarity 73, member A | Hermansky-Pudlak syndrome 5; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Regulates intracellular vesicular trafficking in fibroblasts. May be involved in the regulation of general functions of integrins | 0.643 |
FAM73A | PFKP | ENSP00000359827 | ENSP00000370517 | family with sequence similarity 73, member A | phosphofructokinase, platelet; Catalyzes the third step of glycolysis, the phosphorylation of fructose-6-phosphate (F6P) by ATP to generate fructose-1,6-bisphosphate (FBP) and ADP | 0.460 |
FAM73A | SLC44A5 | ENSP00000359827 | ENSP00000359892 | family with sequence similarity 73, member A | solute carrier family 44, member 5 | 0.457 |
FAM73A | TMC5 | ENSP00000359827 | ENSP00000379531 | family with sequence similarity 73, member A | transmembrane channel-like 5; Probable ion channel (By similarity) | 0.477 |
FAM73A | ZNF683 | ENSP00000359827 | ENSP00000344095 | family with sequence similarity 73, member A | zinc finger protein 683; May be involved in transcriptional regulation | 0.586 |
HNRNPA0 | FAM73A | ENSP00000316042 | ENSP00000359827 | heterogeneous nuclear ribonucleoprotein A0; mRNA-binding component of ribonucleosomes. Specifically binds AU-rich element (ARE)-containing mRNAs. Involved in post- transcriptional regulation of cytokines mRNAs | family with sequence similarity 73, member A | 0.505 |
HPS5 | AGPS | ENSP00000265967 | ENSP00000264167 | Hermansky-Pudlak syndrome 5; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Regulates intracellular vesicular trafficking in fibroblasts. May be involved in the regulation of general functions of integrins | alkylglycerone phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids (By similarity) | 0.483 |
HPS5 | DNAJC14 | ENSP00000265967 | ENSP00000316240 | Hermansky-Pudlak syndrome 5; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Regulates intracellular vesicular trafficking in fibroblasts. May be involved in the regulation of general functions of integrins | DnaJ (Hsp40) homolog, subfamily C, member 14; Regulates the export of target proteins, such as DRD1, from the endoplasmic reticulum to the cell surface (By similarity) | 0.449 |