FAM73A protein (Homo sapiens) - STRING network view

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FAM73A

family with sequence similarity 73, member A (632 aa)

Predicted Functional Partners:

HPS5

0.643

BLMH

0.591

ZNF683

0.586

AGPS

0.533

HNRNPA0

0.505

ENSG00000257390

0.497

DNAJC14

0.497

TMC5

0.477

PFKP

0.460

SLC44A5

0.457

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGPS	FAM73A	ENSP00000264167	ENSP00000359827	alkylglycerone phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids (By similarity)	family with sequence similarity 73, member A	0.533
AGPS	HPS5	ENSP00000264167	ENSP00000265967	alkylglycerone phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids (By similarity)	Hermansky-Pudlak syndrome 5; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Regulates intracellular vesicular trafficking in fibroblasts. May be involved in the regulation of general functions of integrins	0.483
BLMH	FAM73A	ENSP00000261714	ENSP00000359827	bleomycin hydrolase; The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B- aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity (By similarity)	family with sequence similarity 73, member A	0.591
DNAJC14	FAM73A	ENSP00000316240	ENSP00000359827	DnaJ (Hsp40) homolog, subfamily C, member 14; Regulates the export of target proteins, such as DRD1, from the endoplasmic reticulum to the cell surface (By similarity)	family with sequence similarity 73, member A	0.497
DNAJC14	HPS5	ENSP00000316240	ENSP00000265967	DnaJ (Hsp40) homolog, subfamily C, member 14; Regulates the export of target proteins, such as DRD1, from the endoplasmic reticulum to the cell surface (By similarity)	Hermansky-Pudlak syndrome 5; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Regulates intracellular vesicular trafficking in fibroblasts. May be involved in the regulation of general functions of integrins	0.449
ENSG00000257390	FAM73A	ENSP00000447000	ENSP00000359827	Uncharacterized protein	family with sequence similarity 73, member A	0.497
ENSG00000257390	HPS5	ENSP00000447000	ENSP00000265967	Uncharacterized protein	Hermansky-Pudlak syndrome 5; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Regulates intracellular vesicular trafficking in fibroblasts. May be involved in the regulation of general functions of integrins	0.449
FAM73A	AGPS	ENSP00000359827	ENSP00000264167	family with sequence similarity 73, member A	alkylglycerone phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids (By similarity)	0.533
FAM73A	BLMH	ENSP00000359827	ENSP00000261714	family with sequence similarity 73, member A	bleomycin hydrolase; The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B- aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity (By similarity)	0.591
FAM73A	DNAJC14	ENSP00000359827	ENSP00000316240	family with sequence similarity 73, member A	DnaJ (Hsp40) homolog, subfamily C, member 14; Regulates the export of target proteins, such as DRD1, from the endoplasmic reticulum to the cell surface (By similarity)	0.497
FAM73A	ENSG00000257390	ENSP00000359827	ENSP00000447000	family with sequence similarity 73, member A	Uncharacterized protein	0.497
FAM73A	HNRNPA0	ENSP00000359827	ENSP00000316042	family with sequence similarity 73, member A	heterogeneous nuclear ribonucleoprotein A0; mRNA-binding component of ribonucleosomes. Specifically binds AU-rich element (ARE)-containing mRNAs. Involved in post- transcriptional regulation of cytokines mRNAs	0.505
FAM73A	HPS5	ENSP00000359827	ENSP00000265967	family with sequence similarity 73, member A	Hermansky-Pudlak syndrome 5; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Regulates intracellular vesicular trafficking in fibroblasts. May be involved in the regulation of general functions of integrins	0.643
FAM73A	PFKP	ENSP00000359827	ENSP00000370517	family with sequence similarity 73, member A	phosphofructokinase, platelet; Catalyzes the third step of glycolysis, the phosphorylation of fructose-6-phosphate (F6P) by ATP to generate fructose-1,6-bisphosphate (FBP) and ADP	0.460
FAM73A	SLC44A5	ENSP00000359827	ENSP00000359892	family with sequence similarity 73, member A	solute carrier family 44, member 5	0.457
FAM73A	TMC5	ENSP00000359827	ENSP00000379531	family with sequence similarity 73, member A	transmembrane channel-like 5; Probable ion channel (By similarity)	0.477
FAM73A	ZNF683	ENSP00000359827	ENSP00000344095	family with sequence similarity 73, member A	zinc finger protein 683; May be involved in transcriptional regulation	0.586
HNRNPA0	FAM73A	ENSP00000316042	ENSP00000359827	heterogeneous nuclear ribonucleoprotein A0; mRNA-binding component of ribonucleosomes. Specifically binds AU-rich element (ARE)-containing mRNAs. Involved in post- transcriptional regulation of cytokines mRNAs	family with sequence similarity 73, member A	0.505
HPS5	AGPS	ENSP00000265967	ENSP00000264167	Hermansky-Pudlak syndrome 5; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Regulates intracellular vesicular trafficking in fibroblasts. May be involved in the regulation of general functions of integrins	alkylglycerone phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids (By similarity)	0.483
HPS5	DNAJC14	ENSP00000265967	ENSP00000316240	Hermansky-Pudlak syndrome 5; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Regulates intracellular vesicular trafficking in fibroblasts. May be involved in the regulation of general functions of integrins	DnaJ (Hsp40) homolog, subfamily C, member 14; Regulates the export of target proteins, such as DRD1, from the endoplasmic reticulum to the cell surface (By similarity)	0.449

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