| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALPP | PIGK | ENSP00000375881 | ENSP00000359848 | alkaline phosphatase, placental | phosphatidylinositol glycan anchor biosynthesis, class K; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein’s C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein | 0.823 |
| GPAA1 | PIGG | ENSP00000347206 | ENSP00000415203 | glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast); Essential for GPI-anchoring of precursor proteins but not for GPI synthesis. Acts before or during formation of the carbonyl intermediate | phosphatidylinositol glycan anchor biosynthesis, class G | 0.419 |
| GPAA1 | PIGK | ENSP00000347206 | ENSP00000359848 | glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast); Essential for GPI-anchoring of precursor proteins but not for GPI synthesis. Acts before or during formation of the carbonyl intermediate | phosphatidylinositol glycan anchor biosynthesis, class K; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein’s C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein | 0.999 |
| GPAA1 | PIGO | ENSP00000347206 | ENSP00000339382 | glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast); Essential for GPI-anchoring of precursor proteins but not for GPI synthesis. Acts before or during formation of the carbonyl intermediate | phosphatidylinositol glycan anchor biosynthesis, class O; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI third mannose which links the GPI-anchor to the C-terminus of the proteins by an amide bond (By similarity) | 0.612 |
| GPAA1 | PIGS | ENSP00000347206 | ENSP00000309430 | glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast); Essential for GPI-anchoring of precursor proteins but not for GPI synthesis. Acts before or during formation of the carbonyl intermediate | phosphatidylinositol glycan anchor biosynthesis, class S; Component of the GPI transamidase complex. Essential for transfer of GPI to proteins, particularly for formation of carbonyl intermediates | 0.997 |
| GPAA1 | PIGT | ENSP00000347206 | ENSP00000279036 | glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast); Essential for GPI-anchoring of precursor proteins but not for GPI synthesis. Acts before or during formation of the carbonyl intermediate | phosphatidylinositol glycan anchor biosynthesis, class T | 0.999 |
| GPAA1 | PIGU | ENSP00000347206 | ENSP00000217446 | glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast); Essential for GPI-anchoring of precursor proteins but not for GPI synthesis. Acts before or during formation of the carbonyl intermediate | phosphatidylinositol glycan anchor biosynthesis, class U; Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI | 0.993 |
| PGAP1 | PIGG | ENSP00000346809 | ENSP00000415203 | post-GPI attachment to proteins 1; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi (By similarity) | phosphatidylinositol glycan anchor biosynthesis, class G | 0.535 |
| PGAP1 | PIGK | ENSP00000346809 | ENSP00000359848 | post-GPI attachment to proteins 1; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi (By similarity) | phosphatidylinositol glycan anchor biosynthesis, class K; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein’s C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein | 0.913 |
| PGAP1 | PIGS | ENSP00000346809 | ENSP00000309430 | post-GPI attachment to proteins 1; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi (By similarity) | phosphatidylinositol glycan anchor biosynthesis, class S; Component of the GPI transamidase complex. Essential for transfer of GPI to proteins, particularly for formation of carbonyl intermediates | 0.903 |
| PGAP1 | PIGT | ENSP00000346809 | ENSP00000279036 | post-GPI attachment to proteins 1; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi (By similarity) | phosphatidylinositol glycan anchor biosynthesis, class T | 0.912 |
| PGAP1 | PIGU | ENSP00000346809 | ENSP00000217446 | post-GPI attachment to proteins 1; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi (By similarity) | phosphatidylinositol glycan anchor biosynthesis, class U; Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI | 0.925 |
| PGAP1 | PLAUR | ENSP00000346809 | ENSP00000339328 | post-GPI attachment to proteins 1; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi (By similarity) | plasminogen activator, urokinase receptor | 0.900 |
| PIGF | PIGG | ENSP00000281382 | ENSP00000415203 | phosphatidylinositol glycan anchor biosynthesis, class F; Involved in GPI-anchor biosynthesis through the transfer of ethanolamine phosphate to the third mannose of GPI (By similarity) | phosphatidylinositol glycan anchor biosynthesis, class G | 0.986 |
| PIGF | PIGK | ENSP00000281382 | ENSP00000359848 | phosphatidylinositol glycan anchor biosynthesis, class F; Involved in GPI-anchor biosynthesis through the transfer of ethanolamine phosphate to the third mannose of GPI (By similarity) | phosphatidylinositol glycan anchor biosynthesis, class K; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein’s C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein | 0.923 |
| PIGF | PIGO | ENSP00000281382 | ENSP00000339382 | phosphatidylinositol glycan anchor biosynthesis, class F; Involved in GPI-anchor biosynthesis through the transfer of ethanolamine phosphate to the third mannose of GPI (By similarity) | phosphatidylinositol glycan anchor biosynthesis, class O; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI third mannose which links the GPI-anchor to the C-terminus of the proteins by an amide bond (By similarity) | 0.986 |
| PIGF | PIGS | ENSP00000281382 | ENSP00000309430 | phosphatidylinositol glycan anchor biosynthesis, class F; Involved in GPI-anchor biosynthesis through the transfer of ethanolamine phosphate to the third mannose of GPI (By similarity) | phosphatidylinositol glycan anchor biosynthesis, class S; Component of the GPI transamidase complex. Essential for transfer of GPI to proteins, particularly for formation of carbonyl intermediates | 0.906 |
| PIGF | PIGT | ENSP00000281382 | ENSP00000279036 | phosphatidylinositol glycan anchor biosynthesis, class F; Involved in GPI-anchor biosynthesis through the transfer of ethanolamine phosphate to the third mannose of GPI (By similarity) | phosphatidylinositol glycan anchor biosynthesis, class T | 0.917 |
| PIGF | PIGU | ENSP00000281382 | ENSP00000217446 | phosphatidylinositol glycan anchor biosynthesis, class F; Involved in GPI-anchor biosynthesis through the transfer of ethanolamine phosphate to the third mannose of GPI (By similarity) | phosphatidylinositol glycan anchor biosynthesis, class U; Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI | 0.926 |
| PIGG | GPAA1 | ENSP00000415203 | ENSP00000347206 | phosphatidylinositol glycan anchor biosynthesis, class G | glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast); Essential for GPI-anchoring of precursor proteins but not for GPI synthesis. Acts before or during formation of the carbonyl intermediate | 0.419 |
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