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STRINGSTRING
MALSU1 MALSU1 ALDH18A1 ALDH18A1 GTPBP5 GTPBP5 MRPL17 MRPL17 MRPL27 MRPL27 MRPL13 MRPL13 RPL11 RPL11 MRPL20 MRPL20 RPL9 RPL9 MRPL2 MRPL2 MRPL11 MRPL11
"GTPBP5" - GTP binding protein 5 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
GTPBP5GTP binding protein 5 (putative); Involved in the ribosome maturation process. Plays a role of GTPase in vitro. When missing, mitochondria elongation and abnormal nuclear morphology are observed (406 aa)    
Predicted Functional Partners:
MRPL27
mitochondrial ribosomal protein L27 (148 aa)
score_image     score_image score_image   score_image   0.879
MRPL20
mitochondrial ribosomal protein L20 (149 aa)
    score_image   score_image   score_image   0.832
ALDH18A1
aldehyde dehydrogenase 18 family, member A1 (795 aa)
score_image           score_image   0.825
RPL11
ribosomal protein L11; Binds to 5S ribosomal RNA (By similarity). Required for rRNA maturation and formation of the 60S ribosomal subunits. Promotes nucleolar location of PML (By similarity) (178 aa)
      score_image score_image   score_image   0.793
MRPL13
mitochondrial ribosomal protein L13 (178 aa)
    score_image score_image score_image   score_image   0.788
MALSU1
mitochondrial assembly of ribosomal large subunit 1; May function as a ribosomal silencing factor. Addition to isolated mitochondrial ribosomal subunits partially inhibits translation. Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome (234 aa)
score_image     score_image     score_image   0.782
MRPL2
mitochondrial ribosomal protein L2 (305 aa)
    score_image score_image score_image   score_image   0.781
RPL9
ribosomal protein L9 (192 aa)
      score_image score_image   score_image   0.775
MRPL17
mitochondrial ribosomal protein L17 (175 aa)
      score_image score_image   score_image   0.767
MRPL11
mitochondrial ribosomal protein L11 (192 aa)
    score_image score_image score_image   score_image   0.767
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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