node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALDH18A1 | GTPBP5 | ENSP00000360268 | ENSP00000359859 | aldehyde dehydrogenase 18 family, member A1 | GTP binding protein 5 (putative); Involved in the ribosome maturation process. Plays a role of GTPase in vitro. When missing, mitochondria elongation and abnormal nuclear morphology are observed | 0.825 |
ALDH18A1 | MALSU1 | ENSP00000360268 | ENSP00000419370 | aldehyde dehydrogenase 18 family, member A1 | mitochondrial assembly of ribosomal large subunit 1; May function as a ribosomal silencing factor. Addition to isolated mitochondrial ribosomal subunits partially inhibits translation. Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome | 0.608 |
ALDH18A1 | MRPL27 | ENSP00000360268 | ENSP00000225969 | aldehyde dehydrogenase 18 family, member A1 | mitochondrial ribosomal protein L27 | 0.623 |
GTPBP5 | ALDH18A1 | ENSP00000359859 | ENSP00000360268 | GTP binding protein 5 (putative); Involved in the ribosome maturation process. Plays a role of GTPase in vitro. When missing, mitochondria elongation and abnormal nuclear morphology are observed | aldehyde dehydrogenase 18 family, member A1 | 0.825 |
GTPBP5 | MALSU1 | ENSP00000359859 | ENSP00000419370 | GTP binding protein 5 (putative); Involved in the ribosome maturation process. Plays a role of GTPase in vitro. When missing, mitochondria elongation and abnormal nuclear morphology are observed | mitochondrial assembly of ribosomal large subunit 1; May function as a ribosomal silencing factor. Addition to isolated mitochondrial ribosomal subunits partially inhibits translation. Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome | 0.782 |
GTPBP5 | MRPL11 | ENSP00000359859 | ENSP00000308897 | GTP binding protein 5 (putative); Involved in the ribosome maturation process. Plays a role of GTPase in vitro. When missing, mitochondria elongation and abnormal nuclear morphology are observed | mitochondrial ribosomal protein L11 | 0.767 |
GTPBP5 | MRPL13 | ENSP00000359859 | ENSP00000306548 | GTP binding protein 5 (putative); Involved in the ribosome maturation process. Plays a role of GTPase in vitro. When missing, mitochondria elongation and abnormal nuclear morphology are observed | mitochondrial ribosomal protein L13 | 0.788 |
GTPBP5 | MRPL17 | ENSP00000359859 | ENSP00000288937 | GTP binding protein 5 (putative); Involved in the ribosome maturation process. Plays a role of GTPase in vitro. When missing, mitochondria elongation and abnormal nuclear morphology are observed | mitochondrial ribosomal protein L17 | 0.767 |
GTPBP5 | MRPL2 | ENSP00000359859 | ENSP00000373404 | GTP binding protein 5 (putative); Involved in the ribosome maturation process. Plays a role of GTPase in vitro. When missing, mitochondria elongation and abnormal nuclear morphology are observed | mitochondrial ribosomal protein L2 | 0.781 |
GTPBP5 | MRPL20 | ENSP00000359859 | ENSP00000341082 | GTP binding protein 5 (putative); Involved in the ribosome maturation process. Plays a role of GTPase in vitro. When missing, mitochondria elongation and abnormal nuclear morphology are observed | mitochondrial ribosomal protein L20 | 0.832 |
GTPBP5 | MRPL27 | ENSP00000359859 | ENSP00000225969 | GTP binding protein 5 (putative); Involved in the ribosome maturation process. Plays a role of GTPase in vitro. When missing, mitochondria elongation and abnormal nuclear morphology are observed | mitochondrial ribosomal protein L27 | 0.879 |
GTPBP5 | RPL11 | ENSP00000359859 | ENSP00000363676 | GTP binding protein 5 (putative); Involved in the ribosome maturation process. Plays a role of GTPase in vitro. When missing, mitochondria elongation and abnormal nuclear morphology are observed | ribosomal protein L11; Binds to 5S ribosomal RNA (By similarity). Required for rRNA maturation and formation of the 60S ribosomal subunits. Promotes nucleolar location of PML (By similarity) | 0.793 |
GTPBP5 | RPL9 | ENSP00000359859 | ENSP00000346022 | GTP binding protein 5 (putative); Involved in the ribosome maturation process. Plays a role of GTPase in vitro. When missing, mitochondria elongation and abnormal nuclear morphology are observed | ribosomal protein L9 | 0.775 |
MALSU1 | ALDH18A1 | ENSP00000419370 | ENSP00000360268 | mitochondrial assembly of ribosomal large subunit 1; May function as a ribosomal silencing factor. Addition to isolated mitochondrial ribosomal subunits partially inhibits translation. Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome | aldehyde dehydrogenase 18 family, member A1 | 0.608 |
MALSU1 | GTPBP5 | ENSP00000419370 | ENSP00000359859 | mitochondrial assembly of ribosomal large subunit 1; May function as a ribosomal silencing factor. Addition to isolated mitochondrial ribosomal subunits partially inhibits translation. Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome | GTP binding protein 5 (putative); Involved in the ribosome maturation process. Plays a role of GTPase in vitro. When missing, mitochondria elongation and abnormal nuclear morphology are observed | 0.782 |
MALSU1 | MRPL27 | ENSP00000419370 | ENSP00000225969 | mitochondrial assembly of ribosomal large subunit 1; May function as a ribosomal silencing factor. Addition to isolated mitochondrial ribosomal subunits partially inhibits translation. Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome | mitochondrial ribosomal protein L27 | 0.566 |
MRPL11 | GTPBP5 | ENSP00000308897 | ENSP00000359859 | mitochondrial ribosomal protein L11 | GTP binding protein 5 (putative); Involved in the ribosome maturation process. Plays a role of GTPase in vitro. When missing, mitochondria elongation and abnormal nuclear morphology are observed | 0.767 |
MRPL11 | MRPL13 | ENSP00000308897 | ENSP00000306548 | mitochondrial ribosomal protein L11 | mitochondrial ribosomal protein L13 | 0.998 |
MRPL11 | MRPL17 | ENSP00000308897 | ENSP00000288937 | mitochondrial ribosomal protein L11 | mitochondrial ribosomal protein L17 | 0.993 |
MRPL11 | MRPL2 | ENSP00000308897 | ENSP00000373404 | mitochondrial ribosomal protein L11 | mitochondrial ribosomal protein L2 | 0.999 |