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STRINGSTRING
POTEI POTEI POTEJ POTEJ POTEE POTEE LONRF2 LONRF2 KCTD3 KCTD3 UBC UBC LRRC40 LRRC40 RNFT2 RNFT2 MRI1 MRI1 RNFT1 RNFT1 POTEF POTEF
"LRRC40" - leucine rich repeat containing 40 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRRC40leucine rich repeat containing 40 (602 aa)    
Predicted Functional Partners:
MRI1
methylthioribose-1-phosphate isomerase homolog (S. cerevisiae); Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover (369 aa)
        score_image       0.995
KCTD3
potassium channel tetramerisation domain containing 3 (815 aa)
        score_image       0.992
UBC
ubiquitin C (685 aa)
        score_image       0.863
RNFT2
ring finger protein, transmembrane 2 (444 aa)
            score_image   0.620
RNFT1
ring finger protein, transmembrane 1 (435 aa)
            score_image   0.539
POTEE
POTE ankyrin domain family member E (1075 aa)
        score_image   score_image   0.526
POTEI
POTE ankyrin domain family, member I (1075 aa)
        score_image   score_image   0.526
POTEJ
POTE ankyrin domain family, member J (1038 aa)
        score_image   score_image   0.526
POTEF
POTE ankyrin domain family, member F (1075 aa)
        score_image   score_image   0.526
LONRF2
LON peptidase N-terminal domain and ring finger 2 (754 aa)
            score_image   0.517
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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