ZNF831 protein (Homo sapiens) - STRING network view

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ZNF831

zinc finger protein 831 (1677 aa)

Predicted Functional Partners:

RTFDC1

0.692

PPP4R1L

0.660

CSTF1

0.647

XRN1

0.543

YDJC

0.531

VAPB

0.527

KDM2A

0.501

FBXL19

0.501

KDM2B

0.501

PTPN23

0.476

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSTF1	PPP4R1L	ENSP00000217109	ENSP00000335579	cleavage stimulation factor, 3’ pre-RNA, subunit 1, 50kDa; One of the multiple factors required for polyadenylation and 3’-end cleavage of mammalian pre-mRNAs. May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA	protein phosphatase 4, regulatory subunit 1-like; May be a regulatory subunit of serine/threonine-protein phosphatase 4	0.459
CSTF1	RTFDC1	ENSP00000217109	ENSP00000023939	cleavage stimulation factor, 3’ pre-RNA, subunit 1, 50kDa; One of the multiple factors required for polyadenylation and 3’-end cleavage of mammalian pre-mRNAs. May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA	replication termination factor 2 domain containing 1	0.772
CSTF1	ZNF831	ENSP00000217109	ENSP00000360069	cleavage stimulation factor, 3’ pre-RNA, subunit 1, 50kDa; One of the multiple factors required for polyadenylation and 3’-end cleavage of mammalian pre-mRNAs. May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA	zinc finger protein 831	0.647
FBXL19	ZNF831	ENSP00000369666	ENSP00000360069	F-box and leucine-rich repeat protein 19; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity)	zinc finger protein 831	0.501
KDM2A	ZNF831	ENSP00000432786	ENSP00000360069	lysine (K)-specific demethylase 2A; Histone demethylase that specifically demethylates ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys- 36’. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at [...]	zinc finger protein 831	0.501
KDM2B	ZNF831	ENSP00000366271	ENSP00000360069	lysine (K)-specific demethylase 2B; Histone demethylase that demethylates ’Lys-4’ and ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 ’Lys-4’ and dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys-36’. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin [...]	zinc finger protein 831	0.501
PPP4R1L	CSTF1	ENSP00000335579	ENSP00000217109	protein phosphatase 4, regulatory subunit 1-like; May be a regulatory subunit of serine/threonine-protein phosphatase 4	cleavage stimulation factor, 3’ pre-RNA, subunit 1, 50kDa; One of the multiple factors required for polyadenylation and 3’-end cleavage of mammalian pre-mRNAs. May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA	0.459
PPP4R1L	RTFDC1	ENSP00000335579	ENSP00000023939	protein phosphatase 4, regulatory subunit 1-like; May be a regulatory subunit of serine/threonine-protein phosphatase 4	replication termination factor 2 domain containing 1	0.655
PPP4R1L	ZNF831	ENSP00000335579	ENSP00000360069	protein phosphatase 4, regulatory subunit 1-like; May be a regulatory subunit of serine/threonine-protein phosphatase 4	zinc finger protein 831	0.660
PTPN23	ZNF831	ENSP00000265562	ENSP00000360069	protein tyrosine phosphatase, non-receptor type 23; May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis	zinc finger protein 831	0.476
RTFDC1	CSTF1	ENSP00000023939	ENSP00000217109	replication termination factor 2 domain containing 1	cleavage stimulation factor, 3’ pre-RNA, subunit 1, 50kDa; One of the multiple factors required for polyadenylation and 3’-end cleavage of mammalian pre-mRNAs. May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA	0.772
RTFDC1	PPP4R1L	ENSP00000023939	ENSP00000335579	replication termination factor 2 domain containing 1	protein phosphatase 4, regulatory subunit 1-like; May be a regulatory subunit of serine/threonine-protein phosphatase 4	0.655
RTFDC1	ZNF831	ENSP00000023939	ENSP00000360069	replication termination factor 2 domain containing 1	zinc finger protein 831	0.692
VAPB	ZNF831	ENSP00000417175	ENSP00000360069	VAMP (vesicle-associated membrane protein)-associated protein B and C; Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation	zinc finger protein 831	0.527
XRN1	ZNF831	ENSP00000264951	ENSP00000360069	5’-3’ exoribonuclease 1; Major 5’-3’ exoribonuclease involved in mRNA decay. Required for the 5’-3’-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS)	zinc finger protein 831	0.543
YDJC	ZNF831	ENSP00000292778	ENSP00000360069	YdjC homolog (bacterial)	zinc finger protein 831	0.531
ZNF831	CSTF1	ENSP00000360069	ENSP00000217109	zinc finger protein 831	cleavage stimulation factor, 3’ pre-RNA, subunit 1, 50kDa; One of the multiple factors required for polyadenylation and 3’-end cleavage of mammalian pre-mRNAs. May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA	0.647
ZNF831	FBXL19	ENSP00000360069	ENSP00000369666	zinc finger protein 831	F-box and leucine-rich repeat protein 19; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity)	0.501
ZNF831	KDM2A	ENSP00000360069	ENSP00000432786	zinc finger protein 831	lysine (K)-specific demethylase 2A; Histone demethylase that specifically demethylates ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys- 36’. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at [...]	0.501
ZNF831	KDM2B	ENSP00000360069	ENSP00000366271	zinc finger protein 831	lysine (K)-specific demethylase 2B; Histone demethylase that demethylates ’Lys-4’ and ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 ’Lys-4’ and dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys-36’. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin [...]	0.501

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