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RBM14-RBM4 RBM14-RBM4 PTBP1 PTBP1 HNRPDL HNRPDL HNRNPC HNRNPC RBM4B RBM4B RAVER2 RAVER2 RBM4 RBM4 C1orf87 C1orf87 UBE2U UBE2U TCTEX1D1 TCTEX1D1 C1orf141 C1orf141
"RAVER2" - ribonucleoprotein, PTB-binding 2 in Homo sapiens
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protein of unknown 3D structure
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
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protein homology
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Score
RAVER2ribonucleoprotein, PTB-binding 2; May bind single stranded nucleic acids (Potential) (678 aa)    
Predicted Functional Partners:
PTBP1
polypyrimidine tract binding protein 1; Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10 (557 aa)
        score_image   score_image   0.827
HNRNPC
heterogeneous nuclear ribonucleoprotein C (C1/C2) (306 aa)
            score_image   0.607
HNRPDL
heterogeneous nuclear ribonucleoprotein D-like; Acts as a transcriptional regulator. Promotes transcription repression. Promotes transcription activation in differentiated myotubes (By similarity). Binds to double- and single-stranded DNA sequences. Binds to the transcription suppressor CATR sequence of the COX5B promoter (By similarity). Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3’-UTR of many proto-oncogenes and cytokine mRNAs. Binds both to nuclear and cytoplasmic poly(A) mRNAs. Binds to poly(G) and poly(A), but not to poly(U) or [...] (420 aa)
            score_image   0.607
RBM4
RNA binding motif protein 4; RNA-binding factor involved in multiple aspects of cellular processes like alternative splicing of pre-mRNA and translation regulation. Modulates alternative 5’-splice site and exon selection. Acts as a muscle cell differentiation-promoting factor. Activates exon skipping of the PTB pre-mRNA during muscle cell differentiation. Antagonizes the activity of the splicing factor PTBP1 to modulate muscle cell-specific exon selection of alpha tropomyosin. Binds to intronic pyrimidine-rich sequence of the TPM1 and MAPT pre-mRNAs. Required for the translational acti [...] (364 aa)
            score_image   0.520
RBM14-RBM4
RBM14-RBM4 readthrough; RNA-binding factor involved in multiple aspects of cellular processes like alternative splicing of pre-mRNA and translation regulation. Modulates alternative 5’-splice site and exon selection. Acts as a muscle cell differentiation-promoting factor. Activates exon skipping of the PTB pre-mRNA during muscle cell differentiation. Antagonizes the activity of the splicing factor PTBP1 to modulate muscle cell-specific exon selection of alpha tropomyosin. Binds to intronic pyrimidine-rich sequence of the TPM1 and MAPT pre-mRNAs. Required for the translational activatio [...] (364 aa)
            score_image   0.484
C1orf87
chromosome 1 open reading frame 87 (546 aa)
            score_image   0.472
C1orf141
chromosome 1 open reading frame 141 (400 aa)
            score_image   0.472
TCTEX1D1
Tctex1 domain containing 1 (179 aa)
            score_image   0.439
UBE2U
ubiquitin-conjugating enzyme E2U (putative); Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity) (226 aa)
            score_image   0.427
RBM4B
RNA binding motif protein 4B; Required for the translational activation of PER1 mRNA in response to circadian clock. Binds directly to the 3’-UTR of the PER1 mRNA (By similarity) (359 aa)
            score_image   0.426
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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