node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANK1 | RHAG | ENSP00000265709 | ENSP00000360217 | ankyrin 1, erythrocytic | Rh-associated glycoprotein; Associated with rhesus blood group antigen expression. May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane | 0.720 |
ANK1 | SLC4A1 | ENSP00000265709 | ENSP00000262418 | ankyrin 1, erythrocytic | solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group); Band 3 is the major integral glycoprotein of the erythrocyte membrane. Band 3 has two functional domains. Its integral domain mediates a 1-1 exchange of inorganic anions across the membrane, whereas its cytoplasmic domain provides binding sites for cytoskeletal proteins, glycolytic enzymes, and hemoglobin | 0.930 |
CD47 | GYPB | ENSP00000355361 | ENSP00000427690 | CD47 molecule; Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integr [...] | glycophorin B (MNS blood group); This protein is a minor sialoglycoprotein in erythrocyte membranes | 0.680 |
CD47 | RHAG | ENSP00000355361 | ENSP00000360217 | CD47 molecule; Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integr [...] | Rh-associated glycoprotein; Associated with rhesus blood group antigen expression. May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane | 0.887 |
GPI | RHAG | ENSP00000405573 | ENSP00000360217 | glucose-6-phosphate isomerase; Besides it’s role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons | Rh-associated glycoprotein; Associated with rhesus blood group antigen expression. May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane | 0.831 |
GYPB | CD47 | ENSP00000427690 | ENSP00000355361 | glycophorin B (MNS blood group); This protein is a minor sialoglycoprotein in erythrocyte membranes | CD47 molecule; Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integr [...] | 0.680 |
GYPB | RHAG | ENSP00000427690 | ENSP00000360217 | glycophorin B (MNS blood group); This protein is a minor sialoglycoprotein in erythrocyte membranes | Rh-associated glycoprotein; Associated with rhesus blood group antigen expression. May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane | 0.889 |
GYPB | SLC4A1 | ENSP00000427690 | ENSP00000262418 | glycophorin B (MNS blood group); This protein is a minor sialoglycoprotein in erythrocyte membranes | solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group); Band 3 is the major integral glycoprotein of the erythrocyte membrane. Band 3 has two functional domains. Its integral domain mediates a 1-1 exchange of inorganic anions across the membrane, whereas its cytoplasmic domain provides binding sites for cytoskeletal proteins, glycolytic enzymes, and hemoglobin | 0.440 |
HBB | RHAG | ENSP00000333994 | ENSP00000360217 | hemoglobin, beta | Rh-associated glycoprotein; Associated with rhesus blood group antigen expression. May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane | 0.912 |
ICAM4 | RHAG | ENSP00000342114 | ENSP00000360217 | intercellular adhesion molecule 4 (Landsteiner-Wiener blood group); ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM4 is also a ligand for alpha-4/beta-1 and alpha-V integrins | Rh-associated glycoprotein; Associated with rhesus blood group antigen expression. May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane | 0.782 |
PIEZO1 | RHAG | ENSP00000301015 | ENSP00000360217 | piezo-type mechanosensitive ion channel component 1; Component of mechanosensitive channel required for the mechanosensitive currents. Plays a key role in epithelial cell adhesion by maintaining integrin activation through R-Ras recruitment to the ER, most probably in its activated state, and subsequent stimulation of calpain signaling | Rh-associated glycoprotein; Associated with rhesus blood group antigen expression. May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane | 0.801 |
PIEZO1 | STOM | ENSP00000301015 | ENSP00000286713 | piezo-type mechanosensitive ion channel component 1; Component of mechanosensitive channel required for the mechanosensitive currents. Plays a key role in epithelial cell adhesion by maintaining integrin activation through R-Ras recruitment to the ER, most probably in its activated state, and subsequent stimulation of calpain signaling | stomatin; Thought to regulate cation conductance. May regulate ASIC2 and ASIC3 gating (By similarity) | 0.811 |
RHAG | ANK1 | ENSP00000360217 | ENSP00000265709 | Rh-associated glycoprotein; Associated with rhesus blood group antigen expression. May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane | ankyrin 1, erythrocytic | 0.720 |
RHAG | CD47 | ENSP00000360217 | ENSP00000355361 | Rh-associated glycoprotein; Associated with rhesus blood group antigen expression. May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane | CD47 molecule; Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integr [...] | 0.887 |
RHAG | GPI | ENSP00000360217 | ENSP00000405573 | Rh-associated glycoprotein; Associated with rhesus blood group antigen expression. May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane | glucose-6-phosphate isomerase; Besides it’s role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons | 0.831 |
RHAG | GYPB | ENSP00000360217 | ENSP00000427690 | Rh-associated glycoprotein; Associated with rhesus blood group antigen expression. May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane | glycophorin B (MNS blood group); This protein is a minor sialoglycoprotein in erythrocyte membranes | 0.889 |
RHAG | HBB | ENSP00000360217 | ENSP00000333994 | Rh-associated glycoprotein; Associated with rhesus blood group antigen expression. May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane | hemoglobin, beta | 0.912 |
RHAG | ICAM4 | ENSP00000360217 | ENSP00000342114 | Rh-associated glycoprotein; Associated with rhesus blood group antigen expression. May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane | intercellular adhesion molecule 4 (Landsteiner-Wiener blood group); ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM4 is also a ligand for alpha-4/beta-1 and alpha-V integrins | 0.782 |
RHAG | PIEZO1 | ENSP00000360217 | ENSP00000301015 | Rh-associated glycoprotein; Associated with rhesus blood group antigen expression. May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane | piezo-type mechanosensitive ion channel component 1; Component of mechanosensitive channel required for the mechanosensitive currents. Plays a key role in epithelial cell adhesion by maintaining integrin activation through R-Ras recruitment to the ER, most probably in its activated state, and subsequent stimulation of calpain signaling | 0.801 |
RHAG | SLC2A14 | ENSP00000360217 | ENSP00000379834 | Rh-associated glycoprotein; Associated with rhesus blood group antigen expression. May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane | solute carrier family 2 (facilitated glucose transporter), member 14; Facilitative glucose transporter (By similarity). May have a specific function related to spermatogenesis | 0.660 |