PDLIM1 protein (Homo sapiens) - STRING network view

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PDLIM1

PDZ and LIM domain 1; Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton (329 aa)

Predicted Functional Partners:

STK35

0.984

ACTN1

0.959

ACTN4

0.909

ACTN2

0.846

RLIM

0.808

CCL1

0.756

SPTAN1

0.733

MARCO

0.720

PHB2

0.659

CLNS1A

0.644

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTN1	ACTN2	ENSP00000377941	ENSP00000355537	actinin, alpha 1; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein	actinin, alpha 2; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein	0.999
ACTN1	ACTN4	ENSP00000377941	ENSP00000252699	actinin, alpha 1; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein	actinin, alpha 4; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation	0.999
ACTN1	PDLIM1	ENSP00000377941	ENSP00000360305	actinin, alpha 1; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein	PDZ and LIM domain 1; Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton	0.959
ACTN1	SPTAN1	ENSP00000377941	ENSP00000361824	actinin, alpha 1; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein	spectrin, alpha, non-erythrocytic 1	0.911
ACTN1	STK35	ENSP00000377941	ENSP00000370891	actinin, alpha 1; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein	serine/threonine kinase 35	0.606
ACTN2	ACTN1	ENSP00000355537	ENSP00000377941	actinin, alpha 2; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein	actinin, alpha 1; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein	0.999
ACTN2	ACTN4	ENSP00000355537	ENSP00000252699	actinin, alpha 2; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein	actinin, alpha 4; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation	0.999
ACTN2	PDLIM1	ENSP00000355537	ENSP00000360305	actinin, alpha 2; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein	PDZ and LIM domain 1; Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton	0.846
ACTN2	SPTAN1	ENSP00000355537	ENSP00000361824	actinin, alpha 2; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein	spectrin, alpha, non-erythrocytic 1	0.909
ACTN2	STK35	ENSP00000355537	ENSP00000370891	actinin, alpha 2; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein	serine/threonine kinase 35	0.560
ACTN4	ACTN1	ENSP00000252699	ENSP00000377941	actinin, alpha 4; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation	actinin, alpha 1; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein	0.999
ACTN4	ACTN2	ENSP00000252699	ENSP00000355537	actinin, alpha 4; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation	actinin, alpha 2; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein	0.999
ACTN4	PDLIM1	ENSP00000252699	ENSP00000360305	actinin, alpha 4; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation	PDZ and LIM domain 1; Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton	0.909
ACTN4	SPTAN1	ENSP00000252699	ENSP00000361824	actinin, alpha 4; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation	spectrin, alpha, non-erythrocytic 1	0.908
ACTN4	STK35	ENSP00000252699	ENSP00000370891	actinin, alpha 4; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation	serine/threonine kinase 35	0.564
CCL1	MARCO	ENSP00000225842	ENSP00000318916	chemokine (C-C motif) ligand 1; Cytokine that is chemotactic for monocytes but not for neutrophils. Binds to CCR8	macrophage receptor with collagenous structure; Pattern recognition receptor (PRR). Binds Gram-positive and Gram-negative bacteria	0.751
CCL1	PDLIM1	ENSP00000225842	ENSP00000360305	chemokine (C-C motif) ligand 1; Cytokine that is chemotactic for monocytes but not for neutrophils. Binds to CCR8	PDZ and LIM domain 1; Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton	0.756
CCL1	PHB2	ENSP00000225842	ENSP00000441875	chemokine (C-C motif) ligand 1; Cytokine that is chemotactic for monocytes but not for neutrophils. Binds to CCR8	prohibitin 2; Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging	0.812
CCL1	SPTAN1	ENSP00000225842	ENSP00000361824	chemokine (C-C motif) ligand 1; Cytokine that is chemotactic for monocytes but not for neutrophils. Binds to CCR8	spectrin, alpha, non-erythrocytic 1	0.816
CLNS1A	PDLIM1	ENSP00000433919	ENSP00000360305	chloride channel, nucleotide-sensitive, 1A; The interaction with Sm proteins inhibits their assembly on U RNA and interferes with snRNP biogenesis. Inhibits the binding of survival motor neuron protein (SMN) to Sm proteins. May participate in cellular volume control by activation of a swelling-induced chloride conductance pathway	PDZ and LIM domain 1; Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton	0.644

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