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STRINGSTRING
ULK2 ULK2 IL36RN IL36RN ARNT2 ARNT2 SSBP3 SSBP3 CBFA2T2 CBFA2T2 TAL1 TAL1 LMO3 LMO3 LDB2 LDB2 LDB1 LDB1 LHX1 LHX1 LHX5 LHX5
"SSBP3" - single stranded DNA binding protein 3 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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white nodes:
second shell of interactors
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Known Interactions
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from curated databases
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experimentally determined
Predicted Interactions
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fusion edge
gene fusions
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gene co-occurrence
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protein homology
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SSBP3single stranded DNA binding protein 3; May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region (By similarity) (388 aa)    
Predicted Functional Partners:
LDB1
LIM domain binding 1; Binds to the LIM domain of a wide variety of LIM domain- containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. Play a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state (By similarity) (411 aa)
        score_image   score_image   0.950
LDB2
LIM domain binding 2; Binds to the LIM domain of a wide variety of LIM domain- containing transcription factors (373 aa)
        score_image   score_image   0.888
TAL1
T-cell acute lymphocytic leukemia 1; Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation (By similarity) (331 aa)
        score_image   score_image   0.823
LHX1
LIM homeobox 1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis (406 aa)
        score_image   score_image   0.654
IL36RN
interleukin 36 receptor antagonist; Is a highly and a specific antagonist of the IL-1 receptor-related protein 2-mediated response to interleukin 1 family member 9 (IL1F9). Could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL- 1R1), that is present in epithelial barriers and takes part in local inflammatory response (155 aa)
        score_image       0.597
ULK2
unc-51-like kinase 2 (C. elegans); Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3- kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy- acts both as a downstream effector and a negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK, also acts as a negative regulator of AMPK through phosphorylation of the AMPK subunits PRKAA1, PRKAB2 and PRKAG1. [...] (1036 aa)
        score_image       0.592
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2; Specifically recognizes the xenobiotic response element (XRE) (717 aa)
        score_image       0.530
CBFA2T2
core-binding factor, runt domain, alpha subunit 2; translocated to, 2 (604 aa)
            score_image   0.525
LHX5
LIM homeobox 5; Plays an essential role in the regulation of neuronal differentiation and migration during development of the central nervous system (402 aa)
        score_image   score_image   0.508
LMO3
LIM domain only 3 (rhombotin-like 2) (145 aa)
        score_image   score_image   0.506
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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