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DLG4 DLG4 CAMK2A CAMK2A GRIN3A GRIN3A GRIN1 GRIN1 CAMK2B CAMK2B GRIN2D GRIN2D GRIN2B GRIN2B ACTN2 ACTN2 GRIN2A GRIN2A CAMK2G CAMK2G AKAP9 AKAP9
"GRIN1" - glutamate receptor, ionotropic, N-methyl D-aspartate 1 in Homo sapiens
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protein of unknown 3D structure
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second shell of interactors
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GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 1 (943 aa)    
Predicted Functional Partners:
GRIN2A
glutamate receptor, ionotropic, N-methyl D-aspartate 2A; NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Activation requires binding of agonist to both types of subunits (1464 aa)
        score_image score_image score_image score_image 0.999
GRIN2B
glutamate receptor, ionotropic, N-methyl D-aspartate 2B; NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death (By similarity) (1484 aa)
        score_image score_image score_image score_image 0.999
DLG4
discs, large homolog 4 (Drosophila); Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity) (767 aa)
        score_image score_image score_image   0.997
CAMK2G
calcium/calmodulin-dependent protein kinase II gamma (556 aa)
        score_image score_image score_image   0.987
GRIN3A
glutamate receptor, ionotropic, N-methyl-D-aspartate 3A; NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine. May play a role in the development of dendritic spines. May play a role in PPP2CB-NMDAR mediated signaling mechanism (By similarity) (1115 aa)
        score_image score_image score_image score_image 0.984
CAMK2A
calcium/calmodulin-dependent protein kinase II alpha; CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity) (489 aa)
        score_image score_image score_image   0.982
GRIN2D
glutamate receptor, ionotropic, N-methyl D-aspartate 2D; NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine (1336 aa)
        score_image score_image score_image score_image 0.976
AKAP9
A kinase (PRKA) anchor protein (yotiao) 9 (3907 aa)
        score_image score_image score_image   0.974
CAMK2B
calcium/calmodulin-dependent protein kinase II beta (666 aa)
        score_image score_image score_image   0.973
ACTN2
actinin, alpha 2; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (894 aa)
        score_image score_image score_image   0.961
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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