node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BRIX1 | DDX27 | ENSP00000338862 | ENSP00000360828 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 | 0.988 |
BRIX1 | DDX54 | ENSP00000338862 | ENSP00000323858 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54; Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors | 0.974 |
BRIX1 | DDX56 | ENSP00000338862 | ENSP00000258772 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | DEAD (Asp-Glu-Ala-Asp) box helicase 56; May play a role in later stages of the processing of the pre-ribosomal particles leading to mature 60S ribosomal subunits. Has intrinsic ATPase activity | 0.986 |
BRIX1 | FTSJ3 | ENSP00000338862 | ENSP00000396673 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | FtsJ homolog 3 (E. coli); Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation | 0.930 |
BRIX1 | KIAA0020 | ENSP00000338862 | ENSP00000380982 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | KIAA0020 | 0.989 |
BRIX1 | NOP2 | ENSP00000338862 | ENSP00000382392 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | NOP2 nucleolar protein homolog (yeast); May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation. May act as ribosomal RNA methyltransferase | 0.994 |
BRIX1 | PES1 | ENSP00000338862 | ENSP00000346725 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | pescadillo ribosomal biogenesis factor 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | 0.994 |
BRIX1 | RBM28 | ENSP00000338862 | ENSP00000223073 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | RNA binding motif protein 28; Nucleolar component of the spliceosomal ribonucleoprotein complexes | 0.994 |
BRIX1 | RPF2 | ENSP00000338862 | ENSP00000402338 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | ribosome production factor 2 homolog (S. cerevisiae) | 0.998 |
BRIX1 | WDR12 | ENSP00000338862 | ENSP00000261015 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | WD repeat domain 12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | 0.998 |
DDX27 | BRIX1 | ENSP00000360828 | ENSP00000338862 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | 0.988 |
DDX27 | DDX54 | ENSP00000360828 | ENSP00000323858 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54; Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors | 0.994 |
DDX27 | DDX56 | ENSP00000360828 | ENSP00000258772 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 | DEAD (Asp-Glu-Ala-Asp) box helicase 56; May play a role in later stages of the processing of the pre-ribosomal particles leading to mature 60S ribosomal subunits. Has intrinsic ATPase activity | 0.993 |
DDX27 | FTSJ3 | ENSP00000360828 | ENSP00000396673 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 | FtsJ homolog 3 (E. coli); Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation | 0.991 |
DDX27 | KIAA0020 | ENSP00000360828 | ENSP00000380982 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 | KIAA0020 | 0.998 |
DDX27 | NOP2 | ENSP00000360828 | ENSP00000382392 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 | NOP2 nucleolar protein homolog (yeast); May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation. May act as ribosomal RNA methyltransferase | 0.997 |
DDX27 | PES1 | ENSP00000360828 | ENSP00000346725 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 | pescadillo ribosomal biogenesis factor 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | 0.994 |
DDX27 | RBM28 | ENSP00000360828 | ENSP00000223073 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 | RNA binding motif protein 28; Nucleolar component of the spliceosomal ribonucleoprotein complexes | 0.995 |
DDX27 | RPF2 | ENSP00000360828 | ENSP00000402338 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 | ribosome production factor 2 homolog (S. cerevisiae) | 0.990 |
DDX27 | WDR12 | ENSP00000360828 | ENSP00000261015 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 | WD repeat domain 12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | 0.997 |