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FTSJ3 FTSJ3 WDR12 WDR12 NOP2 NOP2 DDX27 DDX27 RPF2 RPF2 DDX54 DDX54 PES1 PES1 KIAA0020 KIAA0020 RBM28 RBM28 DDX56 DDX56 BRIX1 BRIX1
"DDX27" - DEAD in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDX27DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 (796 aa)    
Predicted Functional Partners:
KIAA0020
KIAA0020 (648 aa)
      score_image score_image   score_image   0.998
NOP2
NOP2 nucleolar protein homolog (yeast); May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation. May act as ribosomal RNA methyltransferase (808 aa)
      score_image score_image   score_image   0.997
WDR12
WD repeat domain 12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome (423 aa)
      score_image score_image   score_image   0.997
RBM28
RNA binding motif protein 28; Nucleolar component of the spliceosomal ribonucleoprotein complexes (759 aa)
      score_image score_image   score_image   0.995
DDX54
DEAD (Asp-Glu-Ala-Asp) box polypeptide 54; Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors (882 aa)
    score_image score_image score_image   score_image score_image 0.994
PES1
pescadillo ribosomal biogenesis factor 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome (588 aa)
      score_image score_image   score_image   0.994
DDX56
DEAD (Asp-Glu-Ala-Asp) box helicase 56; May play a role in later stages of the processing of the pre-ribosomal particles leading to mature 60S ribosomal subunits. Has intrinsic ATPase activity (547 aa)
    score_image score_image score_image   score_image score_image 0.993
FTSJ3
FtsJ homolog 3 (E. coli); Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation (847 aa)
      score_image score_image   score_image   0.991
RPF2
ribosome production factor 2 homolog (S. cerevisiae) (306 aa)
      score_image score_image   score_image   0.990
BRIX1
BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit (353 aa)
      score_image score_image   score_image   0.988
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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