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STRINGSTRING
VPS25 VPS25 ENSG00000213297 ENSG00000213297 ZNF625 ZNF625 CTNNBIP1 CTNNBIP1 BEND5 BEND5 BEND4 BEND4 MAP1LC3A MAP1LC3A BUD31 BUD31 TRIML1 TRIML1 BEND6 BEND6
"BEND5" - BEN domain containing 5 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BEND5BEN domain containing 5 (421 aa)    
Predicted Functional Partners:
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha; Involved in formation of autophagosomal vacuoles (autophagosomes) (125 aa)
        score_image       0.665
BUD31
BUD31 homolog (S. cerevisiae) (144 aa)
        score_image       0.551
ENSG00000213297
Zinc finger protein 625 (125 aa)
            score_image   0.509
ZNF625
zinc finger protein 625; May be involved in transcriptional regulation (372 aa)
            score_image   0.509
TRIML1
tripartite motif family-like 1; Probable E3 ubiquitin-protein ligase which plays an important role in blastocyst development (By similarity) (468 aa)
            score_image   0.479
VPS25
vacuolar protein sorting 25 homolog (S. cerevisiae); Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. The ESCRT-II complex may be involved [...] (176 aa)
        score_image       0.469
BEND4
BEN domain containing 4 (534 aa)
            score_image   0.440
BEND6
BEN domain containing 6 (279 aa)
            score_image   0.416
CTNNBIP1
catenin, beta interacting protein 1; Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway (81 aa)
        score_image       0.410
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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