| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DNAAF1 | DNAAF2 | ENSP00000367815 | ENSP00000298292 | dynein, axonemal, assembly factor 1; Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli | dynein, axonemal, assembly factor 2; Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment | 0.680 |
| DNAAF1 | DNAAF3 | ENSP00000367815 | ENSP00000375599 | dynein, axonemal, assembly factor 1; Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli | dynein, axonemal, assembly factor 3; Required for the assembly of axonemal inner and outer dynein arms. Involved in preassembly of dyneins into complexes before their transport into cilia | 0.701 |
| DNAAF1 | DNAH5 | ENSP00000367815 | ENSP00000265104 | dynein, axonemal, assembly factor 1; Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli | dynein, axonemal, heavy chain 5; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required for structural and functional integrity of the cilia of ependymal cells lining the brain ventricles | 0.815 |
| DNAAF1 | DNAI1 | ENSP00000367815 | ENSP00000242317 | dynein, axonemal, assembly factor 1; Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli | dynein, axonemal, intermediate chain 1; Part of the dynein complex of respiratory cilia | 0.763 |
| DNAAF1 | DNAI2 | ENSP00000367815 | ENSP00000308312 | dynein, axonemal, assembly factor 1; Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli | dynein, axonemal, intermediate chain 2; Part of the dynein complex of respiratory cilia | 0.865 |
| DNAAF1 | NME8 | ENSP00000367815 | ENSP00000199447 | dynein, axonemal, assembly factor 1; Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli | NME/NM23 family member 8; Probably required during the final stages of sperm tail maturation in the testis and/or epididymis, where extensive disulfide bonding of fibrous sheath (FS) proteins occurs. May be involved in the reduction of disulfide bonds within the sperm FS components. In vitro, it has neither NDP kinase nor reducing activity on disulfide bonds | 0.608 |
| DNAAF1 | RSPH4A | ENSP00000367815 | ENSP00000229554 | dynein, axonemal, assembly factor 1; Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli | radial spoke head 4 homolog A (Chlamydomonas); Probable component of the axonemal radial spoke head. Radial spokes are regularly spaced along cilia, sperm and flagella axonemes. They consist of a thin stalk which is attached to a subfiber of the outer doublet microtubule, and a bulbous head which is attached to the stalk and appears to interact with the projections from the central pair of microtubules | 0.693 |
| DNAAF1 | RSPH9 | ENSP00000367815 | ENSP00000361238 | dynein, axonemal, assembly factor 1; Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli | radial spoke head 9 homolog (Chlamydomonas); Probable component of the axonemal radial spoke head. Radial spokes are regularly spaced along cilia, sperm and flagella axonemes. They consist of a thin stalk, which is attached to a subfiber of the outer doublet microtubule, and a bulbous head, which is attached to the stalk and appears to interact with the projections from the central pair of microtubules | 0.676 |
| DNAAF2 | DNAAF1 | ENSP00000298292 | ENSP00000367815 | dynein, axonemal, assembly factor 2; Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment | dynein, axonemal, assembly factor 1; Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli | 0.680 |
| DNAAF2 | DNAAF3 | ENSP00000298292 | ENSP00000375599 | dynein, axonemal, assembly factor 2; Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment | dynein, axonemal, assembly factor 3; Required for the assembly of axonemal inner and outer dynein arms. Involved in preassembly of dyneins into complexes before their transport into cilia | 0.764 |
| DNAAF2 | DNAH5 | ENSP00000298292 | ENSP00000265104 | dynein, axonemal, assembly factor 2; Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment | dynein, axonemal, heavy chain 5; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required for structural and functional integrity of the cilia of ependymal cells lining the brain ventricles | 0.669 |
| DNAAF2 | DNAI1 | ENSP00000298292 | ENSP00000242317 | dynein, axonemal, assembly factor 2; Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment | dynein, axonemal, intermediate chain 1; Part of the dynein complex of respiratory cilia | 0.757 |
| DNAAF2 | DNAI2 | ENSP00000298292 | ENSP00000308312 | dynein, axonemal, assembly factor 2; Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment | dynein, axonemal, intermediate chain 2; Part of the dynein complex of respiratory cilia | 0.791 |
| DNAAF2 | NME8 | ENSP00000298292 | ENSP00000199447 | dynein, axonemal, assembly factor 2; Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment | NME/NM23 family member 8; Probably required during the final stages of sperm tail maturation in the testis and/or epididymis, where extensive disulfide bonding of fibrous sheath (FS) proteins occurs. May be involved in the reduction of disulfide bonds within the sperm FS components. In vitro, it has neither NDP kinase nor reducing activity on disulfide bonds | 0.693 |
| DNAAF2 | RSPH4A | ENSP00000298292 | ENSP00000229554 | dynein, axonemal, assembly factor 2; Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment | radial spoke head 4 homolog A (Chlamydomonas); Probable component of the axonemal radial spoke head. Radial spokes are regularly spaced along cilia, sperm and flagella axonemes. They consist of a thin stalk which is attached to a subfiber of the outer doublet microtubule, and a bulbous head which is attached to the stalk and appears to interact with the projections from the central pair of microtubules | 0.753 |
| DNAAF2 | RSPH9 | ENSP00000298292 | ENSP00000361238 | dynein, axonemal, assembly factor 2; Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment | radial spoke head 9 homolog (Chlamydomonas); Probable component of the axonemal radial spoke head. Radial spokes are regularly spaced along cilia, sperm and flagella axonemes. They consist of a thin stalk, which is attached to a subfiber of the outer doublet microtubule, and a bulbous head, which is attached to the stalk and appears to interact with the projections from the central pair of microtubules | 0.681 |
| DNAAF3 | DNAAF1 | ENSP00000375599 | ENSP00000367815 | dynein, axonemal, assembly factor 3; Required for the assembly of axonemal inner and outer dynein arms. Involved in preassembly of dyneins into complexes before their transport into cilia | dynein, axonemal, assembly factor 1; Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli | 0.701 |
| DNAAF3 | DNAAF2 | ENSP00000375599 | ENSP00000298292 | dynein, axonemal, assembly factor 3; Required for the assembly of axonemal inner and outer dynein arms. Involved in preassembly of dyneins into complexes before their transport into cilia | dynein, axonemal, assembly factor 2; Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment | 0.764 |
| DNAAF3 | DNAH5 | ENSP00000375599 | ENSP00000265104 | dynein, axonemal, assembly factor 3; Required for the assembly of axonemal inner and outer dynein arms. Involved in preassembly of dyneins into complexes before their transport into cilia | dynein, axonemal, heavy chain 5; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required for structural and functional integrity of the cilia of ependymal cells lining the brain ventricles | 0.661 |
| DNAAF3 | DNAI1 | ENSP00000375599 | ENSP00000242317 | dynein, axonemal, assembly factor 3; Required for the assembly of axonemal inner and outer dynein arms. Involved in preassembly of dyneins into complexes before their transport into cilia | dynein, axonemal, intermediate chain 1; Part of the dynein complex of respiratory cilia | 0.677 |
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