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STRINGSTRING
COL14A1 COL14A1 COL4A1 COL4A1 COL4A6 COL4A6 COL16A1 COL16A1 COL15A1 COL15A1 COL4A3 COL4A3 COL6A3 COL6A3 COL1A1 COL1A1 COL5A1 COL5A1 COL4A2 COL4A2 COL4A5 COL4A5
"COL4A6" - collagen, type IV, alpha 6 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
COL4A6collagen, type IV, alpha 6 (1691 aa)    
Predicted Functional Partners:
COL4A1
collagen, type IV, alpha 1; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen (1669 aa)
        score_image score_image score_image score_image 0.962
COL4A5
collagen, type IV, alpha 5; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen (1691 aa)
  score_image       score_image score_image score_image 0.935
COL1A1
collagen, type I, alpha 1 (1464 aa)
          score_image score_image   0.931
COL15A1
collagen, type XV, alpha 1; Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle (1388 aa)
          score_image score_image   0.929
COL16A1
collagen, type XVI, alpha 1; Involved in mediating cell attachment and inducing integrin-mediated cellular reactions, such as cell spreading and alterations in cell morphology (1604 aa)
          score_image score_image   0.927
COL14A1
collagen, type XIV, alpha 1 (1796 aa)
          score_image score_image   0.921
COL4A2
collagen, type IV, alpha 2; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen (1712 aa)
          score_image score_image score_image 0.919
COL4A3
collagen, type IV, alpha 3 (Goodpasture antigen) (1670 aa)
          score_image score_image score_image 0.916
COL5A1
collagen, type V, alpha 1; Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin (1838 aa)
          score_image score_image score_image 0.914
COL6A3
collagen, type VI, alpha 3; Collagen VI acts as a cell-binding protein (3177 aa)
          score_image score_image score_image 0.912
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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