TMEM53 protein (Homo sapiens) - STRING network view

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TMEM53

transmembrane protein 53 (277 aa)

Predicted Functional Partners:

TMEM209

0.752

MAGT1

0.681

SCCPDH

0.618

GPR156

0.594

NUP205

0.582

C1orf228

0.569

SLC16A9

0.560

SLC24A3

0.537

PI4K2B

0.520

GPR83

0.518

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C1orf228	TMEM53	ENSP00000420716	ENSP00000361311	chromosome 1 open reading frame 228	transmembrane protein 53	0.569
GPR156	GPR83	ENSP00000324553	ENSP00000243673	G protein-coupled receptor 156; Orphan receptor	G protein-coupled receptor 83; Orphan receptor. Could be a neuropeptide Y receptor	0.513
GPR156	PI4K2B	ENSP00000324553	ENSP00000264864	G protein-coupled receptor 156; Orphan receptor	phosphatidylinositol 4-kinase type 2 beta; Together with PI4K2A and the type III PI4Ks (PIK4CA and PIK4CB) it contributes to the overall PI4-kinase activity of the cell. This contribution may be especially significant in plasma membrane, endosomal and Golgi compartments. The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3). Contributes to the production of InsP3 in stimulated cells and is likely to be involved in the [...]	0.406
GPR156	SLC16A9	ENSP00000324553	ENSP00000378756	G protein-coupled receptor 156; Orphan receptor	solute carrier family 16, member 9 (monocarboxylic acid transporter 9); Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates (By similarity)	0.451
GPR156	TMEM53	ENSP00000324553	ENSP00000361311	G protein-coupled receptor 156; Orphan receptor	transmembrane protein 53	0.594
GPR83	GPR156	ENSP00000243673	ENSP00000324553	G protein-coupled receptor 83; Orphan receptor. Could be a neuropeptide Y receptor	G protein-coupled receptor 156; Orphan receptor	0.513
GPR83	SLC16A9	ENSP00000243673	ENSP00000378756	G protein-coupled receptor 83; Orphan receptor. Could be a neuropeptide Y receptor	solute carrier family 16, member 9 (monocarboxylic acid transporter 9); Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates (By similarity)	0.432
GPR83	TMEM53	ENSP00000243673	ENSP00000361311	G protein-coupled receptor 83; Orphan receptor. Could be a neuropeptide Y receptor	transmembrane protein 53	0.518
MAGT1	NUP205	ENSP00000354649	ENSP00000285968	magnesium transporter 1; May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells	nucleoporin 205kDa; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor NUP62 and other nucleoporins, but not NUP153 and TPR, to the NPC	0.568
MAGT1	SCCPDH	ENSP00000354649	ENSP00000355467	magnesium transporter 1; May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells	saccharopine dehydrogenase (putative)	0.582
MAGT1	TMEM209	ENSP00000354649	ENSP00000380747	magnesium transporter 1; May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells	transmembrane protein 209	0.753
MAGT1	TMEM53	ENSP00000354649	ENSP00000361311	magnesium transporter 1; May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells	transmembrane protein 53	0.681
NUP205	MAGT1	ENSP00000285968	ENSP00000354649	nucleoporin 205kDa; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor NUP62 and other nucleoporins, but not NUP153 and TPR, to the NPC	magnesium transporter 1; May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells	0.568
NUP205	SCCPDH	ENSP00000285968	ENSP00000355467	nucleoporin 205kDa; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor NUP62 and other nucleoporins, but not NUP153 and TPR, to the NPC	saccharopine dehydrogenase (putative)	0.501
NUP205	TMEM209	ENSP00000285968	ENSP00000380747	nucleoporin 205kDa; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor NUP62 and other nucleoporins, but not NUP153 and TPR, to the NPC	transmembrane protein 209	0.759
NUP205	TMEM53	ENSP00000285968	ENSP00000361311	nucleoporin 205kDa; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor NUP62 and other nucleoporins, but not NUP153 and TPR, to the NPC	transmembrane protein 53	0.582
PI4K2B	GPR156	ENSP00000264864	ENSP00000324553	phosphatidylinositol 4-kinase type 2 beta; Together with PI4K2A and the type III PI4Ks (PIK4CA and PIK4CB) it contributes to the overall PI4-kinase activity of the cell. This contribution may be especially significant in plasma membrane, endosomal and Golgi compartments. The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3). Contributes to the production of InsP3 in stimulated cells and is likely to be involved in the [...]	G protein-coupled receptor 156; Orphan receptor	0.406
PI4K2B	TMEM53	ENSP00000264864	ENSP00000361311	phosphatidylinositol 4-kinase type 2 beta; Together with PI4K2A and the type III PI4Ks (PIK4CA and PIK4CB) it contributes to the overall PI4-kinase activity of the cell. This contribution may be especially significant in plasma membrane, endosomal and Golgi compartments. The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3). Contributes to the production of InsP3 in stimulated cells and is likely to be involved in the [...]	transmembrane protein 53	0.520
SCCPDH	MAGT1	ENSP00000355467	ENSP00000354649	saccharopine dehydrogenase (putative)	magnesium transporter 1; May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells	0.582
SCCPDH	NUP205	ENSP00000355467	ENSP00000285968	saccharopine dehydrogenase (putative)	nucleoporin 205kDa; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor NUP62 and other nucleoporins, but not NUP153 and TPR, to the NPC	0.501

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