| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BAX | BCL2 | ENSP00000293288 | ENSP00000329623 | BCL2-associated X protein | B-cell CLL/lymphoma 2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) | 0.999 |
| BAX | BCL2A1 | ENSP00000293288 | ENSP00000267953 | BCL2-associated X protein | BCL2-related protein A1; Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection (By similarity) | 0.648 |
| BAX | BCL2L1 | ENSP00000293288 | ENSP00000302564 | BCL2-associated X protein | BCL2-like 1; Potent inhibitor of cell death. Inhibits activation of caspases (By similarity). Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis | 0.999 |
| BAX | SPATA25 | ENSP00000293288 | ENSP00000361597 | BCL2-associated X protein | spermatogenesis associated 25; May play a role in spermatogenesis | 0.570 |
| BCL2 | BAX | ENSP00000329623 | ENSP00000293288 | B-cell CLL/lymphoma 2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) | BCL2-associated X protein | 0.999 |
| BCL2 | BCL2A1 | ENSP00000329623 | ENSP00000267953 | B-cell CLL/lymphoma 2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) | BCL2-related protein A1; Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection (By similarity) | 0.925 |
| BCL2 | BCL2L1 | ENSP00000329623 | ENSP00000302564 | B-cell CLL/lymphoma 2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) | BCL2-like 1; Potent inhibitor of cell death. Inhibits activation of caspases (By similarity). Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis | 0.996 |
| BCL2 | SPATA25 | ENSP00000329623 | ENSP00000361597 | B-cell CLL/lymphoma 2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) | spermatogenesis associated 25; May play a role in spermatogenesis | 0.412 |
| BCL2A1 | BAX | ENSP00000267953 | ENSP00000293288 | BCL2-related protein A1; Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection (By similarity) | BCL2-associated X protein | 0.648 |
| BCL2A1 | BCL2 | ENSP00000267953 | ENSP00000329623 | BCL2-related protein A1; Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection (By similarity) | B-cell CLL/lymphoma 2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) | 0.925 |
| BCL2A1 | SPATA25 | ENSP00000267953 | ENSP00000361597 | BCL2-related protein A1; Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection (By similarity) | spermatogenesis associated 25; May play a role in spermatogenesis | 0.412 |
| BCL2L1 | BAX | ENSP00000302564 | ENSP00000293288 | BCL2-like 1; Potent inhibitor of cell death. Inhibits activation of caspases (By similarity). Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis | BCL2-associated X protein | 0.999 |
| BCL2L1 | BCL2 | ENSP00000302564 | ENSP00000329623 | BCL2-like 1; Potent inhibitor of cell death. Inhibits activation of caspases (By similarity). Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis | B-cell CLL/lymphoma 2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) | 0.996 |
| BCL2L1 | SPATA25 | ENSP00000302564 | ENSP00000361597 | BCL2-like 1; Potent inhibitor of cell death. Inhibits activation of caspases (By similarity). Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis | spermatogenesis associated 25; May play a role in spermatogenesis | 0.736 |
| BNC2 | SPATA25 | ENSP00000370047 | ENSP00000361597 | basonuclin 2; Probable transcription factor specific for skin keratinocytes. May play a role in the differentiation of spermatozoa and oocytes | spermatogenesis associated 25; May play a role in spermatogenesis | 0.412 |
| SPATA25 | BAX | ENSP00000361597 | ENSP00000293288 | spermatogenesis associated 25; May play a role in spermatogenesis | BCL2-associated X protein | 0.570 |
| SPATA25 | BCL2 | ENSP00000361597 | ENSP00000329623 | spermatogenesis associated 25; May play a role in spermatogenesis | B-cell CLL/lymphoma 2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) | 0.412 |
| SPATA25 | BCL2A1 | ENSP00000361597 | ENSP00000267953 | spermatogenesis associated 25; May play a role in spermatogenesis | BCL2-related protein A1; Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection (By similarity) | 0.412 |
| SPATA25 | BCL2L1 | ENSP00000361597 | ENSP00000302564 | spermatogenesis associated 25; May play a role in spermatogenesis | BCL2-like 1; Potent inhibitor of cell death. Inhibits activation of caspases (By similarity). Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis | 0.736 |
| SPATA25 | BNC2 | ENSP00000361597 | ENSP00000370047 | spermatogenesis associated 25; May play a role in spermatogenesis | basonuclin 2; Probable transcription factor specific for skin keratinocytes. May play a role in the differentiation of spermatozoa and oocytes | 0.412 |
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