ZMAT1 protein (Homo sapiens) - STRING network view

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Size

small nodes:
protein of unknown 3D structure

large nodes:
some 3D structure is known or predicted

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ZMAT1

zinc finger, matrin-type 1 (638 aa)

Predicted Functional Partners:

H1FX

0.554

KCNG4

0.514

ZNF836

0.511

STXBP4

0.482

RCHY1

0.474

ZNF322

0.470

WDR90

0.414

ENSG00000267179

0.407

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSG00000267179	ZMAT1	ENSP00000467286	ENSP00000361868	Zinc finger protein 763 ; May be involved in transcriptional regulation	zinc finger, matrin-type 1	0.407
H1FX	ZMAT1	ENSP00000329662	ENSP00000361868	H1 histone family, member X; Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures	zinc finger, matrin-type 1	0.554
KCNG4	RCHY1	ENSP00000312129	ENSP00000321239	potassium voltage-gated channel, subfamily G, member 4; Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values	ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase; Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Monoubiquitinates the translesion DNA polymerase POLH. Contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity	0.490
KCNG4	STXBP4	ENSP00000312129	ENSP00000365530	potassium voltage-gated channel, subfamily G, member 4; Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values	syntaxin binding protein 4; Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose (By similarity)	0.519
KCNG4	ZMAT1	ENSP00000312129	ENSP00000361868	potassium voltage-gated channel, subfamily G, member 4; Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values	zinc finger, matrin-type 1	0.514
KCNG4	ZNF836	ENSP00000312129	ENSP00000325038	potassium voltage-gated channel, subfamily G, member 4; Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values	zinc finger protein 836; May be involved in transcriptional regulation	0.412
RCHY1	KCNG4	ENSP00000321239	ENSP00000312129	ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase; Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Monoubiquitinates the translesion DNA polymerase POLH. Contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity	potassium voltage-gated channel, subfamily G, member 4; Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values	0.490
RCHY1	STXBP4	ENSP00000321239	ENSP00000365530	ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase; Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Monoubiquitinates the translesion DNA polymerase POLH. Contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity	syntaxin binding protein 4; Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose (By similarity)	0.429
RCHY1	ZMAT1	ENSP00000321239	ENSP00000361868	ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase; Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Monoubiquitinates the translesion DNA polymerase POLH. Contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity	zinc finger, matrin-type 1	0.474
STXBP4	KCNG4	ENSP00000365530	ENSP00000312129	syntaxin binding protein 4; Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose (By similarity)	potassium voltage-gated channel, subfamily G, member 4; Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values	0.519
STXBP4	RCHY1	ENSP00000365530	ENSP00000321239	syntaxin binding protein 4; Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose (By similarity)	ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase; Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Monoubiquitinates the translesion DNA polymerase POLH. Contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity	0.429
STXBP4	ZMAT1	ENSP00000365530	ENSP00000361868	syntaxin binding protein 4; Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose (By similarity)	zinc finger, matrin-type 1	0.482
WDR90	ZMAT1	ENSP00000293879	ENSP00000361868	WD repeat domain 90	zinc finger, matrin-type 1	0.414
ZMAT1	ENSG00000267179	ENSP00000361868	ENSP00000467286	zinc finger, matrin-type 1	Zinc finger protein 763 ; May be involved in transcriptional regulation	0.407
ZMAT1	H1FX	ENSP00000361868	ENSP00000329662	zinc finger, matrin-type 1	H1 histone family, member X; Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures	0.554
ZMAT1	KCNG4	ENSP00000361868	ENSP00000312129	zinc finger, matrin-type 1	potassium voltage-gated channel, subfamily G, member 4; Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values	0.514
ZMAT1	RCHY1	ENSP00000361868	ENSP00000321239	zinc finger, matrin-type 1	ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase; Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Monoubiquitinates the translesion DNA polymerase POLH. Contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity	0.474
ZMAT1	STXBP4	ENSP00000361868	ENSP00000365530	zinc finger, matrin-type 1	syntaxin binding protein 4; Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose (By similarity)	0.482
ZMAT1	WDR90	ENSP00000361868	ENSP00000293879	zinc finger, matrin-type 1	WD repeat domain 90	0.414
ZMAT1	ZNF322	ENSP00000361868	ENSP00000418897	zinc finger, matrin-type 1	zinc finger protein 322; Involved in transcriptional regulation as an activator	0.470

page 1 of 2

Textmining

Cooccurrence

Experiments

Neighborhood

Databases

Fusion

Coexpression

© STRING Consortium 2017

Credits

Access

Info

About