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STRINGSTRING
COLQ COLQ OGFOD2 OGFOD2 DERA DERA CERCAM CERCAM GOPC GOPC OS9 OS9 UBC UBC ZNHIT2 ZNHIT2 PVRL4 PVRL4
"CERCAM" - cerebral endothelial cell adhesion molecule in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CERCAMcerebral endothelial cell adhesion molecule (595 aa)    
Predicted Functional Partners:
OS9
osteosarcoma amplified 9, endoplasmic reticulum lectin (667 aa)
        score_image   score_image   0.790
UBC
ubiquitin C (685 aa)
        score_image       0.633
GOPC
golgi-associated PDZ and coiled-coil motif containing; Plays a role in intracellular protein trafficking and degradation. May regulate CFTR chloride currents and acid-induced ASIC3 currents by modulating cell surface expression of both channels. May also regulate the intracellular trafficking of the ADR1B receptor. May play a role in autophagy. Overexpression results in CFTR intracellular retention and degradation in the lysosomes (462 aa)
        score_image       0.549
COLQ
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase (455 aa)
            score_image   0.536
PVRL4
poliovirus receptor-related 4; Seems to be involved in cell adhesion through trans- homophilic and -heterophilic interactions, the latter including specifically interactions with PVRL2/nectin-1. Does not act as receptor for alpha-herpesvirus entry into cells (510 aa)
            score_image   0.484
DERA
deoxyribose-phosphate aldolase (putative); Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) (318 aa)
            score_image   0.452
ZNHIT2
zinc finger, HIT-type containing 2 (403 aa)
            score_image   0.443
OGFOD2
2-oxoglutarate and iron-dependent oxygenase domain containing 2 (290 aa)
            score_image   0.426
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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